Synonym: (2S,5R,6R)-6-[[(2R)-Carboxy-3-thienylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid disodium salt
CAS Number: 4697-14-7
Empirical Formula (Hill Notation): C15H14N2Na2O6S2
Molecular Weight: 428.39
MDL Number: MFCD07787410
Linear Formula: C15H14N2Na2O6S2
Product Type: Chemical
antibiotic activity spectrum |
Gram-negative bacteria |
|
Gram-positive bacteria |
biological source |
semisynthetic |
color |
white to light yellow |
form |
powder or crystals |
InChI |
1S/C15H16N2O6S2.2Na/c1-15(2)9(14(22)23)17-11(19)8(12(17)25-15)16-10(18)7(13(20)21)6-3-4-24-5-6;;/h3-5,7-9,12H,1-2H3,(H,16,18)(H,20,21)(H,22,23);;/q;2*+1/p-2/t7-,8-,9+,12-;;/m1../s1 |
InChI key |
ZBBCUBMBMZNEME-QBGWIPKPSA-L |
mode of action |
cell wall synthesis | interferes |
Quality Level |
200 ![External link](https://krackeler.com/images/sigma/ext-link.gif) |
SMILES string |
[Na+].[Na+].CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](C([O-])=O)c3ccsc3)C(=O)N2[C@H]1C([O-])=O |
storage condition |
(Keep container tightly closed in a dry and well-ventilated place. Moisture sensitive. Keep in a dry place.) |
storage temp. |
2-8°C |
Application: |
Ticarcillin is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria. It is commonly used in combination with clavulanate in order to improve it′s efficacy. It is used to study appropriate dosing in pediatric patients who have cystic fibrosis. |
Biochem/physiol Actions: |
Ticarcillin is a β-Lactam antibiotic that prevents bacterial cell wall biosynthesis at the level of peptidogylcan cross-linking by inhibiting peptidoglycan transpeptidases. It is derived from penicillin and is similar to carbenicillin in action. Ticarcillin is susceptible to degradation by ß-lactamases. |
General description: |
Chemical structure: ß-lactam |
Other Notes: |
β-Lactam antibiotic |
Other Notes: |
Keep container tightly closed in a dry and well-ventilated place. Moisture sensitive. Keep in a dry place. |
Packaging: |
1G |
Storage Temp. |
2-8°C |
UNSPSC |
51101500 |