Synonym: 2,4,6-Trimethyl-N-(3-trifluoromethyl-phenyl)-benzenesulfonamide; N-(3-Trifluoromethylphenyl)-2,4,6-trimethylbenzenesulfonamide
CAS Number: 200933-14-8
Empirical Formula (Hill Notation): C16H16F3NO2S
Molecular Weight: 343.36
MDL Number: MFCD00095824
Linear Formula: C16H16F3NO2S
Product Type: Chemical
assay |
>97% (HPLC) |
color |
white |
form |
powder |
InChI |
1S/C16H16F3NO2S/c1-10-7-11(2)15(12(3)8-10)23(21,22)20-14-6-4-5-13(9-14)16(17,18)19/h4-9,20H,1-3H3 |
InChI key |
ZIIUUSVHCHPIQD-UHFFFAOYSA-N |
mp |
114-114.8 °C (lit.) |
SMILES string |
Cc1cc(C)c(c(C)c1)S(=O)(=O)Nc2cccc(c2)C(F)(F)F |
solubility |
DMSO: >20 mg/mL |
Application: |
m-3M3FBS has been used for MAP kinase assay in 293T cells. It has also been used for intracellular calcium analysis1. Furthermore, it has been used (at a conc. of 1 μM) as a PLC activator for sensitizing TRPA1 in HEK293t cells2. |
Biochem/physiol Actions: |
First known direct activator of phospholipase C (activates β2, β3, γ1, γ2, δ1 isoforms). |
Packaging: |
10 mg in glass bottle |
Preparation Note: |
m-3M3FBS is soluble in DMSO at a concentration that is greater than 20 mg/ml. |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
>97% (HPLC) |
mp |
114-114.8 °C (lit.) |
UNSPSC |
41106300 |