Testosterone 3-(O-carboxymethyl)oxime: BSA - fluorescein isothiocyanate conjugate
SIGMA/T5771
MDL Number: MFCD00132415
Product Type: Chemical
| assay | ≥98.00% (TLC) |
| drug control | regulated under CDSA - not available from Sigma-Aldrich Canada |
| extent of labeling | ~10 mol steroid per mol BSA |
| ~3 mol FITC per mol BSA | |
| form | powder |
| Quality Level | 200  |
| shipped in | ambient |
| solubility | water: 1.90-2.10 mg/mL, clear to faintly hazy, orange |
| storage temp. | 2-8°C |
| technique(s) | flow cytometry: suitable |
| Application: | Testosterone 3-(O-carboxymethyl)oxime: BSA-FITC has been used for flow cytometric assays in serum-free cell cultures2. It has also been used for fluorescence labeling experiments in L6 cells3. |
| Biochem/physiol Actions: | Studies have reported that BSA-coupled testosterone can block the growth of LNCaP cells. Furthermore, it can activate Fas protein and cell death, as well as reduce the translocation, adhesion and incursion of iAR-negative, DU145 prostate cancer cells2. |
| Packaging: | 5 mg in glass bottle |
| Symbol |   GHS07,GHS08 |
| Signal word | Warning |
| Hazard statements | H302 + H312 + H332 - H351 |
| Precautionary statements | P201 - P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313 |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-40 |
| Safety Statements | 36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98.00% (TLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |