Trazodone hydrochloride
SIGMA/T6154 - ≥99% (HPLC), powder
Synonym: 2-
CAS Number: 25332-39-2
Empirical Formula (Hill Notation): C19H22ClN5O · HCl
Molecular Weight: 408.32
EC Number: 246-855-5
MDL Number: MFCD00079603
Linear Formula: C19H22ClN5O · HCl
Product Type: Chemical
assay | ≥99% (HPLC) |
form | powder |
InChI | 1S/C19H22ClN5O.ClH/c20-16 |
InChI key | OHHDIOKRWWOXMT-UHFFFAOYSA |
originator | Bristol-Myers Squibb |
Quality Level | 200 ![]() |
SMILES string | Cl[H].Clc1cccc(c1)N2CCN(C |
solubility | 0.1 M HCl: soluble 7.4 mg/mL |
45% (w/v) aq 2-hydroxypropyl-β-cyclode |
|
DMSO: soluble | |
H2O: soluble, hazy, colorless | |
methanol: soluble 25 mg/mL, clear, colorless |
Biochem/physiol Actions: | Antidepressant that potentiates the activity of serotonin uptake blockers and has full 5-HT2C serotonin receptor agonist activity. It is metabolized to the 5-HT1 serotonin receptor agonist 1-(3-Chlorophenyl)piperaz |
Features and Benefits: | This compound is featured on the Biogenic Amine Transporters ![]() ![]() |
Features and Benefits: | This compound was developed by Bristol-Myers Squibb ![]() ![]() |
Packaging: | 1, 5 g in glass bottle |
Preparation Note: | Trazodone hydrochloride dissolves in methanol at 25 mg/ml to yield a clear, colorless solution. It also dissolves in water at 50 mg/ml, with heating to yield a hazy colorless solution. Furthermore, the product is soluble in DMSO or in 0.1 N HCl (7.4 mg/ml). The solubility in a 45% (w/v) aqueous 2-hydroxpropyl-β-cyclodex |
Symbol | ![]() ![]() |
Signal word | Warning |
Hazard statements | H302 - H351 |
Precautionary statements | P201 - P301 + P312 + P330 - P308 + P313 |
Hazard Codes | Xn |
Risk Statements | 22-40 |
Safety Statements | 22-36 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥99% (HPLC) |
UNSPSC | 12352200 |