Advanced Search



THI

SIGMA/T6330

Synonym: 2-ATHBI; 2-Acetyl-4-tetrahydroxybutyl Imidazole; 1-[5-[(1R,2S,3R)-1,2,3,4-tetrahydroxybutyl]-1H-imidazol-2-yl]-ethanone

CAS Number: 94944-70-4
Empirical Formula (Hill Notation): C9H14N2O5
Molecular Weight: 230.22
MDL Number: MFCD08752516
Linear Formula: C9H14N2O5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-T6330-1MG 1 mg
 $232.00
1/EA		 Add To Favorites
45-T6330-5MG 5 mg
 $941.00
1/EA		 Add To Favorites
45-T6330-25MG 25 mg
 $1960.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts T6330-25MG.

 

color white to light brown
form powder
InChI 1S/C9H14N2O5/c1-4(13)9-10-2-5(11-9)7(15)8(16)6(14)3-12/h2,6-8,12,14-16H,3H2,1H3,(H,10,11)/t6-,7-,8-/m1/s1
InChI key CQSIXFHVGKMLGQ-BWZBUEFSSA-N
Quality Level 100 
SMILES string CC(=O)c1nc(c[nH]1)[C@@H](O)[C@H](O)[C@H](O)CO
solubility DMSO: 2 mg/mL, clear (warmed)
storage temp. 2-8°C
Biochem/physiol Actions: 2-Acetyl-4-tetrahydroxybutyl imidazole (THI) is known to induce peripheral blood lymphopenia in rats. Studies in rats have also reported that THI can affect lymphocyte migration and degradation.
Biochem/physiol Actions: THI is an inhibitor of sphingosine-1-phosphate lyase and acts as an immunosuppressant.
Biochem/physiol Actions: THI is an inhibitor of sphingosine-1-phosphate lyase and acts as an immunosuppressant. Sphingosine-1-phosphate (S1P) lyase catalyzes the irreversible decomposition of S1P to hexadecanaldehyde and phosphoethanolamine. Reducing S1P lyase activity results in therapeutic levels of immunosuppression without the non-lymphoid lesions that result from synthetic S1P receptor agonists.
Packaging: 1, 5, 25 mg in glass bottle
Preparation Note: THI is soluble in DMSO at a concentration that is greater than 5 mg/ml.
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Hazard Codes Xn
Risk Statements 22
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. 2-8°C
UNSPSC 12352211

The following items have been added to your cart:

Choose a favorite list for this item:
Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Year Price Updates

We are currently working diligently to update our website pricing information for the New Year. If you place an order, you will be acknowledged with any corrected pricing. If you'd like the most current information sooner, please don't hesitate to drop us an email or give us a call and we'd be happy to assist. Thank you for your patience while we are updating.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top