Triamcinolone

SIGMA/T6376

Synonym: 9α-Fluoro-11β,16α,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione; 9α-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione; Fluoxyprednisolone

CAS Number: 124-94-7
Empirical Formula (Hill Notation): C₂₁H₂₇FO₆
Molecular Weight: 394.43
EC Number: 204-718-7
MDL Number: MFCD00010477
Linear Formula: C₂₁H₂₇FO₆
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-T6376-50MG	50 mg	$38.10 1/EA	Add To Favorites
45-T6376-250MG	250 mg	$111.00 1/EA	Add To Favorites
45-T6376-1G	1 g	$316.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T6376-1G

Properties
Descriptions
Safety Info.
Basic Data

InChI	1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28,17(27)10-23)19(14,2)9-16(26)20(13,18)22/h5-7,13-16,23,25-26,28H,3-4,8-10H2,1-2H3/t13-,14-,15+,16-,18-,19-,20-,21-/m0/s1
InChI key	GFNANZIMVAIWHM-OBYCQNJPSA-N
mp	262-263 °C (lit.)
originator	Abbott
Quality Level	100
SMILES string	[H][C@@]12C[C@@H](O)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C
solubility	DMF: soluble 20 mg/mL
	DMSO: soluble (Refer citation 16)
	methanol: soluble 5 mg/mL

Application:	Triamcinolone has been used as a corticosteroid standard for LC-MS-MS analysis. Triamcinolone has also been used to study its effect on IgG and IgE levels in peripheral blood mononuclear cells (PBMCs)
Biochem/physiol Actions:	Triamcinolone is a synthetic glucocorticoid agonist; induces gene expression and apoptosis; inhibits prostaglandin synthesis; impairs tumor necrosis factor (TNF)-α-induced degradation of κB-α; potentiates the differentiation-inducing effects of bone morphogenetic proteins (BMP-2, -4, -6).
Features and Benefits:	This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits:	This compound was developed by Abbott . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging:	1, 5 g in glass bottle
Packaging:	50, 250 mg in glass insert

Symbol	GHS08
Signal word	Warning
Hazard statements	H351
Precautionary statements	P281
Hazard Codes	Xn
Risk Statements	40
Safety Statements	22-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3

mp	262-263 °C (lit.)
UNSPSC	12352200

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