Synonym: 9α-Fluoro-11β,16α,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione; 9α-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione; Fluoxyprednisolone
CAS Number: 124-94-7
Empirical Formula (Hill Notation): C21H27FO6
Molecular Weight: 394.43
EC Number: 204-718-7
MDL Number: MFCD00010477
Linear Formula: C21H27FO6
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T6376-1G
InChI |
1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28,17(27)10-23)19(14,2)9-16(26)20(13,18)22/h5-7,13-16,23,25-26,28H,3-4,8-10H2,1-2H3/t13-,14-,15+,16-,18-,19-,20-,21-/m0/s1 |
InChI key |
GFNANZIMVAIWHM-OBYCQNJPSA-N |
mp |
262-263 °C (lit.) |
originator |
Abbott |
Quality Level |
100 ![External link](https://krackeler.com/images/sigma/ext-link.gif) |
SMILES string |
[H][C@@]12C[C@@H](O)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C |
solubility |
DMF: soluble 20 mg/mL |
|
DMSO: soluble (Refer citation 16) |
|
methanol: soluble 5 mg/mL |
Application: |
Triamcinolone has been used as a corticosteroid standard for LC-MS-MS analysis. Triamcinolone has also been used to study its effect on IgG and IgE levels in peripheral blood mononuclear cells (PBMCs) |
Biochem/physiol Actions: |
Triamcinolone is a synthetic glucocorticoid agonist; induces gene expression and apoptosis; inhibits prostaglandin synthesis; impairs tumor necrosis factor (TNF)-α-induced degradation of κB-α; potentiates the differentiation-inducing effects of bone morphogenetic proteins (BMP-2, -4, -6). |
Features and Benefits: |
This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
Features and Benefits: |
This compound was developed by Abbott . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
Packaging: |
1, 5 g in glass bottle |
Packaging: |
50, 250 mg in glass insert |
Symbol |
GHS08 |
Signal word |
Warning |
Hazard statements |
H351 |
Precautionary statements |
P281 |
Hazard Codes |
Xn |
Risk Statements |
40 |
Safety Statements |
22-36 |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
mp |
262-263 °C (lit.) |
UNSPSC |
12352200 |