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Triamcinolone

SIGMA/T6376

Synonym: 9α-Fluoro-11β,16α,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione; 9α-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione; Fluoxyprednisolone

CAS Number: 124-94-7
Empirical Formula (Hill Notation): C21H27FO6
Molecular Weight: 394.43
EC Number: 204-718-7
MDL Number: MFCD00010477
Linear Formula: C21H27FO6
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-T6376-50MG 50 mg
 $34.50
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45-T6376-250MG 250 mg
 $100.00
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45-T6376-1G 1 g
 $287.00
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45-T6376-5G 5 g
 $1150.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T6376-1G

 

InChI 1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28,17(27)10-23)19(14,2)9-16(26)20(13,18)22/h5-7,13-16,23,25-26,28H,3-4,8-10H2,1-2H3/t13-,14-,15+,16-,18-,19-,20-,21-/m0/s1
InChI key GFNANZIMVAIWHM-OBYCQNJPSA-N
mp 262-263 °C (lit.)
originator Abbott
Quality Level 100 
SMILES string [H][C@@]12C[C@@H](O)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C
solubility DMF: soluble 20 mg/mL
  DMSO: soluble (Refer citation 16)
  methanol: soluble 5 mg/mL
Application: Triamcinolone has been used as a corticosteroid standard for LC-MS-MS analysis. Triamcinolone has also been used to study its effect on IgG and IgE levels in peripheral blood mononuclear cells (PBMCs)
Biochem/physiol Actions: Triamcinolone is a synthetic glucocorticoid agonist; induces gene expression and apoptosis; inhibits prostaglandin synthesis; impairs tumor necrosis factor (TNF)-α-induced degradation of κB-α; potentiates the differentiation-inducing effects of bone morphogenetic proteins (BMP-2, -4, -6).
Features and Benefits: This compound is featured on the Nuclear Receptors (Steroids)  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits: This compound was developed by Abbott . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 1, 5 g in glass bottle
Packaging: 50, 250 mg in glass insert
Symbol GHS08  GHS08
Signal word Warning
Hazard statements H351
Precautionary statements P281
Hazard Codes Xn
Risk Statements 40
Safety Statements 22-36
RIDADR NONH for all modes of transport
WGK Germany WGK 3
mp 262-263 °C (lit.)
UNSPSC 12352200

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