Anti-τ (Tau) antibody produced in rabbit
SIGMA/T6402 - whole antiserum
Synonym: Anti-DDPAC; Anti-FTDP-17; Anti-MAPTL; Anti-MSTD; Anti-MTBT1; Anti-MTBT2; Anti-PPND; Anti-PPP1R103; Anti-TAU; Anti-tau-40
MDL Number: MFCD00164745
Product Type: Chemical
Western Blotting Whole extract of Mouse brain were separated on SDS-PAGE and probed with Anti-Tau antibody produced in Rabbit (Cat. No. T6402). The antibody was developed using 1:10,000 Anti-Rabbit IgG (whole molecule)-Peroxidase antibody produced in Goat (Cat. No. A0545). Lanes 1. 100 antibody 2. 200 antibody 3. Negative Control
| antibody form | whole antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| contains | 15 mM sodium azide |
| Quality Level | 200  |
| shipped in | dry ice |
| species reactivity | chicken, rat, mouse |
| storage temp. | −20°C |
| technique(s) | western blot: 1:100 using rat or mouse brain tissue extract |
| UniProt accession no. | P19332  |
| Application: | Anti-τ (Tau) antibody produced in rabbit has been used as a primary antibody in western blotting. |
| Biochem/physiol Actions: | Removal of Tau (τ) results in developmental delay and learning disability. It participates in the pathology of Alzheimer′s disease (AD). Tau helps in the assembly and maintenance of microtubule structure. |
| Biochem/physiol Actions: | Variation in the MAPT gene encoding tau protein results in frontotemporal dementia. Tau protein acts as a substrate for many kinases. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Tau (τ), also known as MAPT (microtubule associated protein tau) is encoded by the gene mapped on human chromosome 17q21.3. It is highly expressed in neurons but is most prominent in axons. |
| General description: | Tau (τ), also known as microtubule associated protein tau (MAPT) is encoded by the gene mapped on human chromosome 17q21.3. It is highly expressed in neurons but is most prominent in axons. Tau is a heat stable microtubule associated protein (MAP) with a molecular weight of 55- 65 kDa. |
| Immunogen: | τ proteins from chicken embryo brain microtubules. |
| Specificity: | The antibody shows wide species reactivity. Anti-τ does not react with MAP1, MAP2 or tubulin. the antibody reacts with τ, one of the two major classes of heat stable microtubule-associated proteins (MAPs). |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |