Tyrphostin RG 13022
SIGMA/T6568 - ≥98%
Synonym: 2-(3,4′-Dimethoxyphenyl)-1-(3″-pyridinyl)acrylonitrile
CAS Number: 136831-48-6
Empirical Formula (Hill Notation): C16H14N2O2
Molecular Weight: 266.29
MDL Number: MFCD00236444
Linear Formula: C16H14N2O2
Product Type: Chemical
assay | ≥98% |
form | solid |
InChI | 1S/C16H14N2O2/c1-19-15-6- |
InChI key | DBGZNJVTHYFQJI-UHFFFAOYSA |
mp | 114-115 °C |
potency | IC50 (3 micromolar for inhibition of EGF-receptor.) |
Quality Level | 200 ![]() |
SMILES string | COc1ccc(cc1OC)C=C(C#N)c |
solubility | DMSO or ethanol: soluble |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Non-phenolic tyrphostin-class tyrosine kinase inhibitor. |
Preparation Note: | Tyrphostin RG 13022 is known to suppress EGF-induced cancer cell proliferation under in vitro conditions and can also inhibit the growth of tumors in nude mice. |
Preparation Note: | Tyrphostin RG 13022 is soluble in DMSO and ethanol. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% |
mp | 114-115 °C |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |