Tandospirone

SIGMA/T6704 - ≥98% (HPLC)

Synonym: (1R*,2S*,3R*,4S*)-N-(4-(4-(2-Pyrimidinyl)-1-piperazinyl)butyl)-2,3-norbornanedicarboximide citrate salt; SM 3997

CAS Number: 87760-53-0
Empirical Formula (Hill Notation): C₂₁H₂₉N₅O₂
Molecular Weight: 383.49
Linear Formula: C₂₁H₂₉N₅O₂
Product Type: Chemical

assay	≥98% (HPLC)
InChI	1S/C21H29N5O2/c27-19-17-15-4-5-16(14-15)18(17)20(28)26(19)9-2-1-8-24-10-12-25(13-11-24)21-22-6-3-7-23-21/h3,6-7,15-18H,1-2,4-5,8-14H2/t15-,16+,17+,18-
InChI key	CEIJFEGBUDEYSX-FZDBZEDMSA-N
originator	Dainippon Sumitomo
Quality Level	100
SMILES string	O=C1[C@@H]2[C@H]3CC[C@H](C3)[C@@H]2C(=O)N1CCCCN4CCN(CC4)c5ncccn5
solubility	DMSO: 38 mg/mL
storage condition	protect from light
storage temp.	2-8°C

Biochem/physiol Actions:	Tandospirone is a partial agonist at 5HT_1A receptors. It significantly reduces haloperidol-induced bradykinesia in a dose-dependent manner. The potency of tandospirone is equal to that of buspirone and approximate half that of diazepam. The potency of tandospirone as a dopamine antagonistic is less than 1/4 that of buspirone.
Features and Benefits:	This compound was developed by Dainippon Sumitomo . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging:	5, 25 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable