Trypsin Acetylated from bovine pancreas
SIGMA/T6763 - Type V-S, ≥8,500 BAEE units/mg protein (biuret)
Synonym: Acetyltrypsin
MDL Number: MFCD00082094
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T6763-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T6763-250MG
| biological source | bovine pancreas |
| form | powder |
| Quality Level | 200  |
| specific activity | ≥8,500 BAEE units/mg protein (biuret) |
| storage temp. | −20°C |
| type | Type V-S |
| UniProt accession no. | Q29463  |
| Application: | Trypsin has been used in a study to assess the ontogeny of the endocrine pancreas in the fetal/newborn baboon. Trypsin digestion and hydrogen/deuterium exchange support the transition between inward- and outward-facing conformations during the catalytic cycle of the bacterial multidrug ATP-binding cassette transporter. |
| Biochem/physiol Actions: | Lys-acetylated trypsin is less susceptible to autolysis than the native form. |
| General description: | The trypsin molecule has two domains: one is related to the enzyme active site and the tryptophan residues; the other is related to the 8-anilinonaphthalene-1-su |
| Other Notes: | One BAEE unit will produce a ΔA253 of 0.001 per min at pH 7.6 at 25° C using BAEE as substrate. Reaction volume = 3.2 mL (1 cm light path). |
| Other Notes: | View more information on trypsin at www.sigma-aldrich.com/enz. |
| Packaging: | 1 g in glass bottle |
| Packaging: | 100, 250 mg in glass bottle |
| Preparation Note: | Prepared by the method of Labouesse, J. and Gervais, M., Eur. J. Biochem., 2, 215 (1967). |
| Symbol |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H315 - H319 - H334 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 36/37/38-42/43 |
| Safety Statements | 22-26-36/37-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| activity | specific activity: ≥8,500 BAEE units/mg protein (biuret) |
| Storage Temp. | −20°C |
| Enzyme Commission (EC) Number | 3.4.21.4 ( BRENDA | IUBMB ) |
| UNSPSC | 12352204 |