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Triprolidine hydrochloride

SIGMA/T6764 - ≥99%

Synonym: (E)-2-[3-(1-Pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride; trans-2-[3-(1-Pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride

CAS Number: 6138-79-0
Empirical Formula (Hill Notation): C19H22N2 · HCl
Molecular Weight: 314.85
MDL Number: MFCD00039044
Linear Formula: C19H22N2 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-T6764-1G 1 g
 $45.50
1/EA		 Add To Favorites
45-T6764-5G 5 g
 $161.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T6764-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T6764-5G

 

assay ≥99%
InChI 1S/C19H22N2.ClH/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21;/h2-3,6-12H,4-5,13-15H2,1H3;1H/b18-11+;
InChI key WYUYEJNGHIOFOC-NWBUNABESA-N
originator GlaxoSmithKline
Quality Level 200 
SMILES string CC(C=C1)=CC=C1/C(C2=NC=CC=C2)=CCN3CCCC3.Cl
solubility alcohol: soluble 1 in 1.5 of solvent
  chloroform: soluble 1 in less than 1 of solvent
  H2O: soluble 50 mg/mL, clear, colorless to yellow
storage temp. 2-8°C
Application: Triprolidine has been used as a H1 histaminergic inhibitor to study its effect on long-term potentiation (LTP) in tuberomammillary nucleus (TMN) neurons.
Biochem/physiol Actions: H1 histamine receptor antagonist.
Features and Benefits: This compound is featured on the Histamine Receptors  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits: This compound was developed by GlaxoSmithKline . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 1, 5 g in poly bottle
Preparation Note: Triprolidine hydrochloride is soluble in water at 50 mg/ml and yields a clear, colorless to yellow solution. It is also soluble in alcohol (1 in 1.5 of solvent) and chloroform (1 in less than 1 of solvent).
Purity ≥99%
Storage Temp. 2-8°C
UNSPSC 12352200

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