Trizma® base
SIGMA/T6791 - BioXtra, pH 10.5-12.0 (1 M in H2O), ≥99.9% (titration)
Synonym: 2-
CAS Number: 77-86-1
Empirical Formula (Hill Notation): C4H11NO3
Molecular Weight: 121.14
EC Number: 201-064-4
MDL Number: MFCD00004679
Linear Formula: NH2C(CH2OH)3
Product Type: Chemical
absorption | ≤0.020 at 280 in H2O at 1 M |
≤0.025 at 260 in H2O at 1 M | |
anion traces | chloride (Cl-): ≤0.005% |
sulfate (SO42-): ≤0.005% | |
application(s) | diagnostic assay manufacturing |
assay | ≥99.9% (titration) |
bp | 219-220 °C/10 mmHg (lit.) |
cation traces | Al: ≤0.0005% |
As: ≤0.0001% | |
Ba: ≤0.0005% | |
Bi: ≤0.0005% | |
Ca: ≤0.001% | |
Cd: ≤0.0005% | |
Co: ≤0.0005% | |
Cr: ≤0.0005% | |
Cu: ≤0.0005% | |
Fe: ≤0.0005% | |
K: ≤0.005% | |
Li: ≤0.0005% | |
Mg: ≤0.0005% | |
Mn: ≤0.0005% | |
Mo: ≤0.0005% | |
Na: ≤0.005% | |
Ni: ≤0.0005% | |
Pb: ≤0.0005% | |
Sr: ≤0.0005% | |
Zn: ≤0.0005% | |
description | aminopeptidase substrate |
form | crystalline |
ign. residue (900°C) | ≤0.01% (as SO4) |
impurities | ≤0.005% Insoluble matter |
InChI | 1S/C4H11NO3/c5-4(1-6,2-7) |
InChI key | LENZDBCJOHFCAS-UHFFFAOYSA |
loss | ≤0.5% loss on drying, 110°C |
mp | 167-172 °C (lit.) |
pH | 10.5-12.0 (1 M in H2O) |
pKa (25 °C) | 8.1 |
product line | BioXtra |
Quality Level | 400 ![]() |
SMILES string | NC(CO)(CO)CO |
solubility | H2O: 1 M, colorless |
useful pH range | 7-9 |
Legal Information: | Trizma is a registered trademark of Sigma-Aldrich Co. LLC |
Other Notes: | Easily compare specifications for Trizma products with the Trizma specification table ![]() |
Other Notes: | The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution. For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode. |
Packaging: | 1 kg in poly bottle |
Packaging: | 100, 500 g in poly bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥99.9% (titration) |
bp | 219-220 °C/10 mmHg (lit.) |
mp | 167-172 °C (lit.) |
UNSPSC | 12352104 |