Thymidine 5′-monophosphate disodium salt hydrate

SIGMA/T7004 - ≥99%

Synonym: 5′-Thymidylic acid disodium salt; TMP; dTMP

CAS Number: 33430-62-5
Empirical Formula (Hill Notation): C₁₀H₁₃N₂Na₂O₈P · xH₂O
Molecular Weight: 366.17 (anhydrous basis)
EC Number: 251-518-0
MDL Number: MFCD09039259
Linear Formula: C₁₀H₁₃N₂Na₂O₈P · xH₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-T7004-100MG	100 mg	$55.20 1/EA	Add To Favorites
45-T7004-250MG	250 mg	$91.20 1/EA	Add To Favorites
45-T7004-1G	1 g	$282.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T7004-100MG

Properties
Descriptions
Safety Info.
Basic Data

assay	≥99%
InChI	1S/C10H15N2O8P.2Na.H2O/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(20-8)4-19-21(16,17)18;;;/h3,6-8,13H,2,4H2,1H3,(H,11,14,15)(H2,16,17,18);;;1H2/q;2*+1;/p-2/t6-,7+,8+;;;/m0.../s1
InChI key	KCOPAVKVHIWPKB-SPSULGLQSA-L
Quality Level	200
SMILES string	O.[Na+].[Na+].CC1=CN([C@H]2C[C@H](O)[C@@H](COP([O-])([O-])=O)O2)C(=O)NC1=O
storage temp.	−20°C

Application:	Thymidine 5′-monophosphate disodium salt hydrate has been used as a standard for the quantification of metabolites from plasma and tumor interstitial fluid using liquid chromatography-mass spectrometry analysis (LC/MS). It has also been used as a single deoxy-mononucleotide to test its effect on the cell growth of human malignant intestinal CaCo-2 cells and normal rat intestinal cell line IEC-6 cells.
Application:	Thymidine 5′-monophosphate disodium salt hydrate has been used as a standard solution.
General description:	Thymidine 5′-monophosphate de novo synthesis from deoxyuridine monophosphate (dUMP) is catalyzed by the enzyme thymidylate synthase.
Other Notes:	Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. T7004.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Packaging:	1 g in poly bottle
Packaging:	100, 250 mg in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99%
Storage Temp.	−20°C
UNSPSC	41106305

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