Tazarotene
SIGMA/T7080 - ≥98% (HPLC)
Synonym: 6-
CAS Number: 118292-40-3
Empirical Formula (Hill Notation): C21H21NO2S
Molecular Weight: 351.46
Linear Formula: C21H21NO2S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to very faintly yellow |
form | powder |
InChI | 1S/C21H21NO2S/c1-4-24-20( |
InChI key | OGQICQVSFDPSEI-UHFFFAOYSA |
originator | Allergan |
Quality Level | 100 ![]() |
solubility | DMSO: >15 mg/mL |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Tazarotene induces the expression of tazarotene-induced gene 3 (TIG3), a tumor suppressor gene. It is a prodrug of tazarotenic acid, which specifically activates RARb and RARg, only weakly activates RARa, and is inactive at retinoid X receptors (RXRs). In psoriasis, tazarotene normalizes abnormal keratinocyte differentiation and reduces their hyperproliferation. |
Features and Benefits: | This compound is a featured product for Gene Regulation research. Click here ![]() ![]() |
Features and Benefits: | This compound was developed by Allergan ![]() ![]() |
Packaging: | 10, 50 mg in glass bottle |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H361d |
Precautionary statements | P201 - P202 - P280 - P308 + P313 - P405 - P501 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |