Synonym: 4,4′-Methylenebis(tetrahydro-1,2,4-sulfadiazine 1,1-dioxide); Taurolin; Tauroline
CAS Number: 19388-87-5
Empirical Formula (Hill Notation): C7H16N4O4S2
Molecular Weight: 284.36
EC Number: 243-016-5
MDL Number: MFCD00865076
Linear Formula: C7H16N4O4S2
Product Type: Chemical
| assay |
>97% (NMR) |
| color |
white to off-white |
| form |
powder |
| InChI |
1S/C7H16N4O4S2/c12-16(13)3-1-10(5-8-16)7-11-2-4-17(14,15)9-6-11/h8-9H,1-7H2 |
| InChI key |
AJKIRUJIDFJUKJ-UHFFFAOYSA-N |
| Quality Level |
100  |
| SMILES string |
O=S1(=O)CCN(CN1)CN2CCS(=O)(=O)NC2 |
| solubility |
DMSO: >20 mg/mL |
| storage condition |
protect from light |
| storage temp. |
room temp |
| Biochem/physiol Actions: |
Taurolidine is a broad spectrum antibiotic with antineoplastic activity, which induces apoptosis and decreases tumor cell proliferation. Taurolidine has been used with TNF-related-apoptosis-inducing ligand (TRAIL) to characterize synergistic responses in many apoptosis related signaling-proteins. Tauroline is also being used as a tool to study the various mechanisms of apoptosis and necrosis. |
| Biochem/physiol Actions: |
Taurolidine is an antibacterial agent that can be used for the treatment of peritonis. It has also been used as an antiendoxic substance for systematic inflammatory response syndrome and as an anti-angiogenic agent for tumors. Furthermore, studies have reported that taurolidine can be used for the prevention of multiple catheter-related bloodstream infections. |
| Packaging: |
5, 25 mg in glass bottle |
| Preparation Note: |
Taurolidine is soluble in DMSO at a concentration that is greater than 20 mg/ml. |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
>97% (NMR) |
| Storage Temp. |
room temp |
| UNSPSC |
12352200 |
