Anti-phospho-Tau (pSer404) antibody produced in rabbit
SIGMA/T7444 - affinity isolated antibody, buffered aqueous glycerol solution
MDL Number: MFCD03097317
Product Type: Chemical
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous glycerol solution |
| Quality Level | 200  |
| shipped in | wet ice |
| species reactivity | mouse, human, rat |
| storage temp. | −20°C |
| technique(s) | immunohistochemistry: suitable |
| western blot: 1:1,000 | |
| UniProt accession no. | P10636  |
| Application: | Anti-phospho-Tau (pSer404) antibody may be used in western blot (1:1000), immunoblot (1:1000) and immunohistochemistry. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Tau is a microtubule-associated phosphoprotein that is present in the axons of nerve cells. It stabilizes microtubules and mediates the polymerization of tubulin. Phosphorylation of Tau regulates its cellular functions. Hyperphosphorylation of Tau has been linked to neurodegenerative disorders such as Alzheimer’s disease . Anti-phospho-Tau (pSer404) antibody specifically reacts with Tau (pSer404) (45-68 kDa) in humans, mice and rats. |
| Immunogen: | chemically synthesized phosphopeptide derived from the region of human tau that contains serine404. |
| Physical form: | Solution in Dulbecco′s phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, with 50% glycerol, 1.0 mg/ml BSA (IgG and protease free) and 0.05% sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |