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Tyrphostin 51

SIGMA/T7665 - ≥98%

Synonym: 2-Amino-1,1,3-tricyano-4-(3′,4′,5′-trihydroxyphenyl)butadiene

CAS Number: 126433-07-6
Empirical Formula (Hill Notation): C13H8N4O3
Molecular Weight: 268.23
MDL Number: MFCD00133903
Linear Formula: C13H8N4O3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-T7665-5MG 5 mg
 $182.00
1/EA		 Add To Favorites
45-T7665-25MG 25 mg
 $581.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T7665-25MG

 

assay ≥98%
biological source synthetic (organic)
form powder
InChI 1S/C13H8N4O3/c14-4-8(12(17)9(5-15)6-16)1-7-2-10(18)13(20)11(19)3-7/h1-3,18-20H,17H2/b8-1+
InChI key JKNOYWVMHPMBEL-UNXLUWIOSA-N
potency 0.8 μM IC50
Quality Level 200 
SMILES string NC(C(=Cc1cc(O)c(O)c(O)c1)C#N)=C(/C#N)C#N
solubility DMSO: soluble 5 mg of Tyrphostin 51 in 0.1 ml of solvent, clear, orange to red
storage temp. 2-8°C
Application: Tyrphostin 51 has been used to study the inhibition of rat hepatic leptin 1.
Biochem/physiol Actions: EGFR tyrosine kinase inhibitor.
Biochem/physiol Actions: Tyrphostin 51 is a small molecule inhibitor of epidermal growth factor (EGF) receptor kinase function. This molecule associates with the substrate subsite of the protein tyrosine kinase (PTK) domain,.
Features and Benefits: This compound is a featured product for Kinase Phosphatase Biology research. Click here  to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Packaging: 25 mg in poly bottle
Packaging: 5 mg in glass bottle
Preparation Note: 5 mg of Tyrphostin 51 is soluble in 0.1 ml of DMSO and yields a clear, orange to red solution.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98%
Storage Temp. 2-8°C
UNSPSC 12352200

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