Synonym: 2-Amino-1,1,3-tricyano-4-(3′,4′,5′-trihydroxyphenyl)butadiene
CAS Number: 126433-07-6
Empirical Formula (Hill Notation): C13H8N4O3
Molecular Weight: 268.23
MDL Number: MFCD00133903
Linear Formula: C13H8N4O3
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T7665-25MG
assay |
≥98% |
biological source |
synthetic (organic) |
form |
powder |
InChI |
1S/C13H8N4O3/c14-4-8(12(17)9(5-15)6-16)1-7-2-10(18)13(20)11(19)3-7/h1-3,18-20H,17H2/b8-1+ |
InChI key |
JKNOYWVMHPMBEL-UNXLUWIOSA-N |
potency |
0.8 μM IC50 |
Quality Level |
200 ![External link](https://krackeler.com/images/sigma/ext-link.gif) |
SMILES string |
NC(C(=Cc1cc(O)c(O)c(O)c1)C#N)=C(/C#N)C#N |
solubility |
DMSO: soluble 5 mg of Tyrphostin 51 in 0.1 ml of solvent, clear, orange to red |
storage temp. |
2-8°C |
Application: |
Tyrphostin 51 has been used to study the inhibition of rat hepatic leptin 1. |
Biochem/physiol Actions: |
EGFR tyrosine kinase inhibitor. |
Biochem/physiol Actions: |
Tyrphostin 51 is a small molecule inhibitor of epidermal growth factor (EGF) receptor kinase function. This molecule associates with the substrate subsite of the protein tyrosine kinase (PTK) domain,. |
Features and Benefits: |
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
Packaging: |
25 mg in poly bottle |
Packaging: |
5 mg in glass bottle |
Preparation Note: |
5 mg of Tyrphostin 51 is soluble in 0.1 ml of DMSO and yields a clear, orange to red solution. |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥98% |
Storage Temp. |
2-8°C |
UNSPSC |
12352200 |