I-OMe-Tyrphostin AG 538

SIGMA/T7697 - solid

Synonym: α-Cyano-(3-methoxy-4-hydroxy-5-iodocinnamoyl)-(3′,4′-dihydroxyphenyl)ketone; I-OMe-AG 538

Empirical Formula (Hill Notation): C₁₇H₁₂INO₅
Molecular Weight: 437.19
MDL Number: MFCD03453582
Linear Formula: C₁₇H₁₂INO₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-T7697-5MG	5 mg	$172.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

form	solid
InChI	1S/C17H12INO5/c1-24-15-6-9(5-12(18)17(15)23)4-11(8-19)16(22)10-2-3-13(20)14(21)7-10/h2-7,20-21,23H,1H3/b11-4+
InChI key	HSRMHXWCTRFVHK-NYYWCZLTSA-N
Quality Level	100
SMILES string	COc1cc(cc(I)c1O)C=C(/C#N)C(=O)c2ccc(O)c(O)c2
solubility	DMSO: 50 mg/mL
storage temp.	−20°C

Application:	I-OMe-Tyrphostin AG 538 has been used as a cell signaling inhibitor in PC-1 cell lines. It has also been used in high throughput screening assays for IGF1R inhibitors.
Biochem/physiol Actions:	Insulin growth factor 1 (IGF-1) receptor protein tyrosine kinase inhibitor.
Features and Benefits:	This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Packaging:	5 mg in glass bottle
Preparation Note:	I-OMe-Tyrphostin AG 538 is soluble in DMSO at 50 mg/ml.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	−20°C
UNSPSC	12352200

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