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I-OMe-Tyrphostin AG 538

SIGMA/T7697 - solid

Synonym: α-Cyano-(3-methoxy-4-hydroxy-5-iodocinnamoyl)-(3′,4′-dihydroxyphenyl)ketone; I-OMe-AG 538

CAS Number: 1094048-77-7
Empirical Formula (Hill Notation): C17H12INO5
Molecular Weight: 437.19
MDL Number: MFCD03453582
Linear Formula: C17H12INO5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-T7697-5MG 5 mg
 $190.00
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This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

form solid
InChI 1S/C17H12INO5/c1-24-15-6-9(5-12(18)17(15)23)4-11(8-19)16(22)10-2-3-13(20)14(21)7-10/h2-7,20-21,23H,1H3/b11-4+
InChI key HSRMHXWCTRFVHK-NYYWCZLTSA-N
Quality Level 100 
SMILES string COc1cc(cc(I)c1O)C=C(/C#N)C(=O)c2ccc(O)c(O)c2
solubility DMSO: 50 mg/mL
storage temp. −20°C
Application: I-OMe-Tyrphostin AG 538 has been used as a cell signaling inhibitor in PC-1 cell lines. It has also been used in high throughput screening assays for IGF1R inhibitors.
Biochem/physiol Actions: Insulin growth factor 1 (IGF-1) receptor protein tyrosine kinase inhibitor.
Features and Benefits: This compound is a featured product for Kinase Phosphatase Biology research. Click here  to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Packaging: 5 mg in glass bottle
Preparation Note: I-OMe-Tyrphostin AG 538 is soluble in DMSO at 50 mg/ml.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. −20°C
UNSPSC 12352203

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