2-Thiouracil
SIGMA/T7750 - ≥99%
Synonym: (2-thioxo -2, 3-
CAS Number: 141-90-2
Empirical Formula (Hill Notation): C4H4N2OS
Molecular Weight: 128.15
EC Number: 205-508-8
MDL Number: MFCD00006039
Linear Formula: C4H4N2OS
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T7750-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T7750-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T7750-250G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T7750-1KG
| assay | ≥99% |
| biological source | synthetic |
| form | powder |
| InChI | 1S/C4H4N2OS/c7-3-1-2-5-4( |
| InChI key | ZEMGGZBWXRYJHK-UHFFFAOYSA |
| mp | >300 °C (lit.) |
| Quality Level | 200  |
| SMILES string | O=C1NC(=S)NC=C1 |
| solubility | 1 M NaOH: 5 mg/mL, clear to very slightly hazy |
| 1 M NaOH: 50 mg/mL, colorless to faintly yellow |
| Application: | 2-Thiouracil may be used: • in the synthesis and characterization of silver colloid and film substrates and their applications in surface-enhanced Raman scattering (SERS) • to study its electro-oxidation and determination at titanium dioxide (TiO2) nanoparticles-modified gold electrode • to study the effect of methylation on the deactivation mechanism or the triplet-state dynamics of 2-thiouracil using time-resolved photoelectron spectroscopy |
| Biochem/physiol Actions: | 2-Thiouracil acts as an anticancer, antithyroid, and antiviral agent. 2-Thiouracil is a selective melanoma-seeker and competitive inhibitor of neuronal nitric oxide synthase. It also forms complexes with transition metals such as gold (Au), chromium (Cr), zinc (Zn), and silver (Ag).2-thiouracil can be incorporated into the tissue culture medium to inhibit virus replication or movement from infected to healthy tissues during chemotherapy. |
| General description: | 2-Thiouracil is a thio-derivative of uracil, a pyrimidine nucleobase.This antithyroid drug has less solubility in H2O & organic solvents. |
| Packaging: | 1 kg in poly bottle |
| Packaging: | 25, 100, 250 g in poly bottle |
| Symbol |  GHS08 |
| Signal word | Warning |
| Hazard statements | H351 |
| Precautionary statements | P281 |
| Hazard Codes | Xn |
| Risk Statements | 40 |
| Safety Statements | 36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% |
| mp | >300 °C (lit.) |
| UNSPSC | 41106305 |