(R)-Tomoxetine hydrochloride
SIGMA/T7947 - solid
Synonym: (R)-N-Methyl-γ-(2-methylÂphenoxy)benzenepropanamine hydrochloride; Atomoxetine hydrochloride
CAS Number: 82248-59-7
Empirical Formula (Hill Notation): C17H21NO · HCl
Molecular Weight: 291.82
MDL Number: MFCD06410992
Linear Formula: C17H21NO · HCl
Product Type: Chemical
form | solid |
InChI | 1S/C17H21NO.ClH/c1-14-8-6 |
InChI key | LUCXVPAZUDVVBT-UNTBIKODSA |
originator | Eli Lilly |
Quality Level | 100 ![]() |
SMILES string | CNCC[C@@H](OC1=CC=CC=C1C) |
storage temp. | 2-8°C |
Application: | (R)-Tomoxetine hydrochloride has been used as a noradrenaline reuptake inhibitor: • to study the role of • to study its effects on set shifting in rats • to study its effects on rat brain as a result of its long-term use |
Biochem/physiol Actions: | (R)-Tomoxetine hydrochloride is an efficient inhibitor of presynaptic norepinephrine transporters. It also positively regulates the release of acetylcholine in the prefrontal cortex (PFC). (R)-Tomoxetine hydrochloride binds to the serotonin (5-HT) transporter. It is involved in blocking the cortical N-methyl- |
Biochem/physiol Actions: | Norepinephrine uptake blocker. |
Features and Benefits: | This compound is featured on the Biogenic Amine Transporters ![]() ![]() |
Features and Benefits: | This compound was developed by Eli Lilly ![]() ![]() |
Packaging: | 25, 50, 100 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |