Advanced Search



(R)-Tomoxetine hydrochloride

SIGMA/T7947 - solid

Synonym: (R)-N-Methyl-γ-(2-methyl­phenoxy)benzenepropanamine hydrochloride; Atomoxetine hydrochloride

CAS Number: 82248-59-7
Empirical Formula (Hill Notation): C17H21NO · HCl
Molecular Weight: 291.82
MDL Number: MFCD06410992
Linear Formula: C17H21NO · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-T7947-25MG 25 mg
 $611.00
1/EA		 Add To Favorites
45-T7947-100MG 100 mg
 $1540.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T7947-25MG

 

form solid
InChI 1S/C17H21NO.ClH/c1-14-8-6-7-11-16(14)19-17(12-13-18-2)15-9-4-3-5-10-15;/h3-11,17-18H,12-13H2,1-2H3;1H/t17-;/m1./s1
InChI key LUCXVPAZUDVVBT-UNTBIKODSA-N
originator Eli Lilly
Quality Level 100 
SMILES string CNCC[C@@H](OC1=CC=CC=C1C)C2=CC=CC=C2.[H]Cl
storage temp. 2-8°C
Application: (R)-Tomoxetine hydrochloride has been used as a noradrenaline reuptake inhibitor:
• to study the role of L-threo-3,4-dihydroxyphenylserine (L-DOPS) in the pathogenesis of Alzheimer′s disease in mice
• to study its effects on set shifting in rats
• to study its effects on rat brain as a result of its long-term use
Biochem/physiol Actions: (R)-Tomoxetine hydrochloride is an efficient inhibitor of presynaptic norepinephrine transporters. It also positively regulates the release of acetylcholine in the prefrontal cortex (PFC). (R)-Tomoxetine hydrochloride binds to the serotonin (5-HT) transporter. It is involved in blocking the cortical N-methyl-D-aspartate (NMDA) receptors.. (R)-Tomoxetine hydrochloride exhibits therapeutic effects against attention-deficit/hyperactivity disorder (ADHD) and comorbid oppositional defiant disorder (ODD).
Biochem/physiol Actions: Norepinephrine uptake blocker.
Features and Benefits: This compound is featured on the Biogenic Amine Transporters  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits: This compound was developed by Eli Lilly . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 25, 50, 100 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. 2-8°C
UNSPSC 12352200

The following items have been added to your cart:

Choose a favorite list for this item:
Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Tariffs & Effects on Pricing

Tariff note: As we navigate the current environment of tariff surcharges and mid-year manufacturer price increases, we want to keep you informed. While we have avoided making specific decisions thus far, we anticipate that we will be forced to implement a cost adjustment policy to offset the fees we have already been absorbing. We are committed to transparency and moderation in this process.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top