Testosterone 3-(O-carboxymethyl)oxime

SIGMA/T8390

Synonym: 17β-Hydroxy-4-androsten-3-one 3-(O-carboxymethyl)oxime; 4-Androsten-17β-ol-3-one 3-(O-carboxymethyl)oxime

CAS Number: 10190-93-9
Empirical Formula (Hill Notation): C₂₁H₃₁NO₄
Molecular Weight: 361.48
MDL Number: MFCD00056503
Linear Formula: C₂₁H₃₁NO₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-T8390-100MG	100 mg	$158.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T8390-100MG

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98.00% (TLC)
drug control	Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
form	powder
InChI	1S/C21H31NO4/c1-20-9-7-14(22-26-12-19(24)25)11-13(20)3-4-15-16-5-6-18(23)21(16,2)10-8-17(15)20/h11,15-18,23H,3-10,12H2,1-2H3,(H,24,25)/b22-14+/t15-,16-,17-,18-,20-,21-/m0/s1
InChI key	VDYLVWGBLQNNAW-UVTKPVMCSA-N
Quality Level	200
shipped in	ambient
SMILES string	[H][C@@]12CCC3=CC(CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@@H](O)CC[C@@]24[H])=NOCC(O)=O
solubility	ethanol: soluble 49-51 mg/mL, clear, colorless to faintly yellow
sterility	non-sterile
storage temp.	room temp

Application:	Testosterone 3-(O-carboxymethyl)oxime has been used for the hormonal analysis of sexual dimorphism in the electric fish, Apteronotus. This testosterone derivative has also been used for developing environmental biosensors for the detection of testosterone in water samples.
Application:	Testosterone 3-(O-carboxymethyl)oxime has been used to prepare horseradish peroxidase (HRP)-labeled testosterone to measure plasma testosterone concentration by enzyme immunoassay.
Biochem/physiol Actions:	Androgens direct the development of male reproductive system and secondary sexual characteristics. Testosterone is an androgen that is secreted by the testis. This hormone is converted to dihydrotestosterone (DHT) by 5α reductase in the target tissues. Both DHT and testosterone require androgen receptor, a ligand-dependent nuclear transcription factor to mediate their biological functions.
Biochem/physiol Actions:	Androgens direct the development of the male phenotype during embryogenesis and at puberty. Testosterone is an androgen that is secreted by the testis. This hormone is converted to dihydrotestosterone in the target tissues where it may mediate several biological functions.
Packaging:	100 mg in glass bottle
Preparation Note:	Testosterone 3-(O-carboxymethyl)oxime is soluble in ethanol at 49-51 mg/ml and yields a clear, colorless to faint yellow solution.

Symbol	GHS07,GHS08
Signal word	Warning
Hazard statements	H302 + H312 + H332 - H351
Precautionary statements	P201 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
Hazard Codes	Xn
Risk Statements	20/21/22-40
Safety Statements	22-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98.00% (TLC)
Storage Temp.	room temp
UNSPSC	12352200

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