L-Threonine
SIGMA/T8441 - from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%
Synonym: (2S,3R)
CAS Number: 72-19-5
Empirical Formula (Hill Notation): C4H9NO3
Molecular Weight: 119.12
EC Number: 200-774-1
MDL Number: MFCD00064270
Linear Formula: CH3CH(OH)CH(NH2)CO2H
Product Type: Chemical
agency | meets EP testing specifications |
meets JP testing specifications | |
meets USP testing specifications | |
USP/NF | |
application(s) | pharmaceutical (small molecule) |
assay | 99.0-101.0% |
biological source | non-animal source |
color | white |
form | powder |
impurities | endotoxin, tested |
InChI | 1S/C4H9NO3/c1-2(6)3(5)4(7 |
InChI key | AYFVYJQAPQTCCC-GBXIJSLDSA |
mp | 256 °C (dec.) (lit.) |
product line | BioXtra |
quality | meets EP, JP, USP testing specifications |
Quality Level | 300 |
SMILES string | C[C@@H](O)[C@H](N)C(O)=O |
solubility | H2O: 1 g/10 mL, clear, colorless |
technique(s) | cell culture | mammalian: suitable |
Application: | L-Threonine has been used for the following : • To study the effect of heat on homoserine kinase activity • In Plackett–Burman analysis and then to study the effect of selected amino acids on monoclonal antibody production in CHO cells • As a substrate to determine the L-threonine dehydrogenase activity • To study the effect of L-Threonine on the growth rate of P. putida, to check for its tolerance towards L-Threonine |
Biochem/physiol Actions: | L-Threonine is considered to be an essential amino acid. L-Threonine is involved in the synthesis of mucin, a protein supporting intestinal function and integrity. L-Threonine is required for the performance of the immune system. It is also essential for O-linked glycosylation, protein phosphorylation and glycine synthesis. |
General description: | |
Packaging: | 1 kg in poly bottle |
Packaging: | 10 mg in glass bottle |
Packaging: | 25, 100 g in poly bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | 99.0-101.0% |
mp | 256 °C (dec.) (lit.) |
UNSPSC | 12352209 |