Tyrosinase Fragment 369-377 human
SIGMA/T8455
Synonym: CMM8; OCA1A; OCAIA; SHEP3; TYR
CAS Number: 168650-46-2
Empirical Formula (Hill Notation): C42H66N10O16S2
Molecular Weight: 1031.16
Linear Formula: C42H66N10O16S2
Product Type: Chemical
assay | 97-100% (HPLC) |
biological source | human |
color | white |
form | lyophilized powder |
Quality Level | 200 ![]() |
shipped in | dry ice |
solubility | deionized water: soluble |
storage temp. | −20°C |
UniProt accession no. | P14679 ![]() ![]() |
Amino Acid Sequence: | Tyr-Met-Asp-Gly-Thr-Met-S |
Application: | Tyrosinase Fragment 369-377 human is a peptide used for controlling the melanin production. |
Biochem/physiol Actions: | The Tyrosinase enzyme catalyzes the first steps in the conversion of tyrosine to melanin. This is a membrane bound enzyme expressed in primary and metastatic melanoma lesions. The Tyrosine fragment 369-377 peptide is presented by HLA-A2 antigen to CTLs. |
Biochem/physiol Actions: | Tyrosinase Fragment 369-377 human is a peptide fragment of enzyme tyrosinase belongs to tyrosinase family. It catalyzes three distinct reactions, the hydroxylation of a monophenol, the dehydrogenation of a catechol and the dehydrogenation of a dihydroxyindole during biosynthesis of melanin. |
Other Notes: | Lyophilized from 0.1% TFA in H2O |
Physical form: | Lyophilized from 0.1% aqueous TFA |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | 97-100% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352202 |