Tyrosinase Fragment 369-377 human
SIGMA/T8455
Synonym: CMM8; OCA1A; OCAIA; SHEP3; TYR
CAS Number: 168650-46-2
Empirical Formula (Hill Notation): C42H66N10O16S2
Molecular Weight: 1031.16
Linear Formula: C42H66N10O16S2
Product Type: Chemical
| assay | 97-100% (HPLC) |
| biological source | human |
| color | white |
| form | lyophilized powder |
| Quality Level | 200  |
| shipped in | dry ice |
| solubility | deionized water: soluble |
| storage temp. | −20°C |
| UniProt accession no. | P14679  |
| Amino Acid Sequence: | Tyr-Met-Asp-Gly-Thr-Met-S |
| Application: | Tyrosinase Fragment 369-377 human is a peptide used for controlling the melanin production. |
| Biochem/physiol Actions: | The Tyrosinase enzyme catalyzes the first steps in the conversion of tyrosine to melanin. This is a membrane bound enzyme expressed in primary and metastatic melanoma lesions. The Tyrosine fragment 369-377 peptide is presented by HLA-A2 antigen to CTLs. |
| Biochem/physiol Actions: | Tyrosinase Fragment 369-377 human is a peptide fragment of enzyme tyrosinase belongs to tyrosinase family. It catalyzes three distinct reactions, the hydroxylation of a monophenol, the dehydrogenation of a catechol and the dehydrogenation of a dihydroxyindole during biosynthesis of melanin. |
| Other Notes: | Lyophilized from 0.1% TFA in H2O |
| Physical form: | Lyophilized from 0.1% aqueous TFA |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 97-100% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |