O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate potassium salt
SIGMA/T8543 - ≥95%, solid
Synonym: D609
CAS Number: 83373-60-8
Empirical Formula (Hill Notation): C11H15KOS2
Molecular Weight: 266.46
EC Number: 280-379-9
MDL Number: MFCD00171401
Linear Formula: C11H15KOS2
Product Type: Chemical
assay | ≥95% |
biological source | synthetic (organic) |
color | off-white to yellow |
form | solid |
InChI | 1S/C11H16OS2.K/c13-11(14) |
InChI key | IGULCCCBGBDZKQ-HJPGVBIPSA |
Quality Level | 200 ![]() |
SMILES string | [K]SC(=S)OC1CC2CC1C3CCCC2 |
solubility | acetone: easily soluble |
diethyl ether: insoluble | |
H2O: soluble 50 mg/mL, clear to slightly hazy, colorless to faintly yellow | |
hydrocarbons: insoluble |
Application: | D609 has been used as a phosphatidylcholine-speci |
Biochem/physiol Actions: | D609 can block the production of diacylglycerol (DAG) in the cell. D609 functions by inhibiting the phospholipase C-mediated hydrolysis of the phosphate bond present in phosphatidylcholine and other glycerophospholipids. |
Biochem/physiol Actions: | Phosphatidylcholine-speci |
Packaging: | 25 mg in poly bottle |
Packaging: | 5 mg in glass bottle |
Preparation Note: | O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate or D609 is soluble in water at 50 mg/ml and yields a clear to slightly hazy, colorless to light yellow solution. It is also soluble in acetone. However, it is insoluble in ether and hydrocarbons. Alcoholic solutions should not be prepared due to the possibility of transesterification. The product is very labile in solution (1.5 days half-life in tissue culture medium) and is readily hydrolyzed below pH 6.0. Hence, solutions should be prepared immediately before use and unused solutions must be discarded. For tissue culture preparations, the media should be buffered to pH 6.0-7.5. HEPES buffer must not be used as it renders this product toxic. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95% |
UNSPSC | 41106300 |