Trichloroacetic acid
SIGMA/T8657 - suitable for electrophoresis, suitable for fixing solution (for IEF and PAGE gels), ≥99%
Synonym: TCA
CAS Number: 76-03-9
Empirical Formula (Hill Notation): C2HCl3O2
Molecular Weight: 163.39
EC Number: 200-927-2
MDL Number: MFCD00004177
Linear Formula: Cl3CCOOH
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T8657-1KG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T8657-500G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T8657-250G
| anion traces | chloride (Cl-): ≤0.001% |
| nitrate (NO3-): ≤0.002% | |
| phosphate (PO43-): ≤5 ppm | |
| sulfate (SO42-): ≤0.02% | |
| application(s) | cell analysis |
| assay | ≥99% |
| bp | 196 °C (lit.) |
| cation traces | Fe: ≤0.0005% |
| heavy metals (as Pb): ≤0.002% | |
| density | 1.62 g/mL at 25 °C (lit.) |
| form | powder or flakes (or crystals) |
| grade | electrophoresis grade |
| InChI | 1S/C2HCl3O2/c3-2(4,5)1(6) |
| InChI key | YNJBWRMUSHSURL-UHFFFAOYSA |
| mp | 54-58 °C (lit.) |
| Quality Level | 200  |
| refractive index | n |
| SMILES string | OC(=O)C(Cl)(Cl)Cl |
| solubility | water: 1 g/mL, clear, colorless |
| storage temp. | 2-8°C |
| suitability | suitable for fixing solution (for IEF and PAGE gels) |
| technique(s) | electrophoresis: suitable |
| turbidity | ≤3 NTU (1 g/ml) |
| vapor density | <1 (vs air) |
| vapor pressure | 1 mmHg ( 51 °C) |
| Application: | Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy. |
| Application: | Trichloroacetic acid has been used: • for hydrolysis of DNA isolated from the cell • for precipitation of glutathione isolated from seminal plasma • as a fixative in microscopy |
| General description: | Trichloroacetic acid (TCA) is produced during the chlorination of water comprising natural organic material. It is a novel reagent used in clinical laboratories for deproteinization of body fluids. In addition, TCA is also used in the treatment of genital warts and acne scars. |
| Packaging: | 1 kg in glass bottle |
| Packaging: | 250, 500 g in glass bottle |
| Symbol |    GHS05,GHS07,GHS09 |
| Signal word | Danger |
| Hazard statements | H314 - H335 - H410 |
| Precautionary statements | P260 - P271 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338 |
| Hazard Codes | C,N |
| Risk Statements | 35-50/53 |
| Safety Statements | 26-36/37/39-45-60-61 |
| RIDADR | UN 1839 8 / PGII |
| WGK Germany | WGK 2 |
| Flash Point(F) | > 235.4 °F - closed cup |
| Flash Point(C) | > 113 °C - closed cup |
| Purity | ≥99% |
| bp | 196 °C (lit.) |
| mp | 54-58 °C (lit.) |
| Density | 1.62 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| Storage Temp. | 2-8°C |
| UNSPSC | 41105319 |