TFIIB human
SIGMA/T8819 - ~5 units/μL, recombinant, expressed in E. coli, solution
MDL Number: MFCD01636087
Product Type: Chemical
| concentration | ~5 units/μL |
| form | solution |
| mol wt | ~32 kDa |
| Quality Level | 200  |
| recombinant | expressed in E. coli |
| shipped in | dry ice |
| storage temp. | −70°C |
| UniProt accession no. | Q00403  |
| Biochem/physiol Actions: | General transcription factor for RNA Polymerase II. |
| Biochem/physiol Actions: | The amino terminal region of TFIIB contains a zinc ribbon fold composed of antiparallel Β strands. Mutational studies show that this domain is required for recruitment of RNA Pol II for transcriptional initiation. |
| Packaging: | 50 units in glass bottle |
| Physical form: | Solution in 20 mM Tris-HCl, pH 7.4, 100 mM NaCl, 2 mM DTT, 1 mM EDTA, 0.1% Triton® X-100. |
| Unit Definition: | One gel shift unit is the amount of TFIIB required to form 0.2 pmol of TFIIB/TFIID/DNA complex as detected by gel shift. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −70°C |
| UNSPSC | 12352202 |