Trypsin inhibitor from chicken egg white
SIGMA/T9253 - Type II-O, Partially purified ovomucoid, containing ovoinhibitor
Synonym: Ovomucoid
CAS Number: 9035-81-8
EC Number: 232-906-9
MDL Number: MFCD00082102
Product Type: Chemical
Trypsin Inhibitor (chicken egg white)
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T9253-5G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T9253-250MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T9253-500MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T9253-1G
| biological source | chicken egg white |
| form | powder |
| mol wt | 14 kDa |
| Quality Level | 200  |
| solubility | water: soluble 10 g/L |
| storage temp. | 2-8°C |
| type | Type II-O |
| Analysis Note: | One mg will inhibit 0.8-1.6 mg of tryspin with activity of approx. 10,000 BAEE units per mg protein. May inhibit ≤0.3 mg of chymotrypsin with activity of approx. 40 BTEE units per mg protein. |
| Application: | Trypsin inhibitor from chicken egg white has been used: • to produce denatured, oxidized and deglycosylated ovomucoid and used to stimulate patient derived cell cultures for mapping T cell epitopes • to treat nuclei for flow cytometric analysis • in Holtfreter′s solution, used for the dissociation of planarians into cells |
| General description: | 25% of ovomucoid comprises carbohydrate. |
| General description: | Ovomucoid or trypsin inhibitor is an abundant protein in most avian egg whites. The hen′s egg protein is composed of about 186 amino acid residues, and is highly glycosylated. Three tandem domains are each homologous with pancreatic trypsin inhibitor. It is highly immunogenic, and probably accounts for most cases of egg allergy. |
| Other Notes: | Ovomucoid, from chicken egg white, does not itself inhibit chymotrypsin. Chymotrypsin inhibition is a measure of ovoinhibitor contamination by method of Feeney, R. E., et al., J. Biol. Chem., 238, 1415 (1963). |
| Other Notes: | View more information on Trypsin Inhibitor . |
| Packaging: | 1, 5 g in poly bottle |
| Packaging: | 250, 500 mg in poly bottle |
| Unit Definition: | One trypsin unit will produce a ΔA253 of 0.001 per min with BAEE as substrate at pH 7.6 at 25 °C; reaction volume 3.2 mL, 1 cm light path. |
| Symbol |  GHS08 |
| Signal word | Danger |
| Hazard statements | H317 - H334 |
| Precautionary statements | P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313 |
| Hazard Codes | Xn |
| Risk Statements | 42/43 |
| Safety Statements | 22-36/37-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352202 |