Tamoxifen citrate salt
SIGMA/T9262 - ≥99%
Synonym: (Z)
CAS Number: 54965-24-1
Empirical Formula (Hill Notation): C26H29NO · C6H8O7
Molecular Weight: 563.64
EC Number: 259-415-2
MDL Number: MFCD00058321
Linear Formula: C26H29NO · C6H8O7
Product Type: Chemical
assay | ≥99% |
InChI | 1S/C26H29NO.C6H8O7/c1-4-2 |
InChI key | FQZYTYWMLGAPFJ-OQKDUQJOSA |
originator | AstraZeneca |
Quality Level | 200 ![]() |
SMILES string | OC(=O)CC(O)(CC(O)=O)C(O)= |
solubility | methanol: soluble 50 mg/mL, clear, colorless |
storage temp. | 2-8°C |
Application: | Tamoxifen has been used for analyzing its effects on radiation sensitivity and steroid receptor content in human breast cancer cells. It has also been used for studying the accumulation of triacylglycerol in hepatic tissues of female rats. Furthermore, studies have reported that environmental magnetic fields can block antiproliferative functions of tamoxifen in human breast cancer cells. |
Biochem/physiol Actions: | Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells. |
Features and Benefits: | This compound is a featured product for ADME Tox research. Click here ![]() ![]() |
Features and Benefits: | This compound is featured on the Nuclear Receptors (Steroids) ![]() ![]() |
Features and Benefits: | This compound was developed by AstraZeneca ![]() ![]() |
Packaging: | 1, 5 g in glass bottle |
Preparation Note: | Tamoxifen citrate salt dissolves in methanol at 50 mg/ml to yield a clear, colorless solution. |
Symbol | ![]() ![]() ![]() |
Signal word | Danger |
Hazard statements | H302 - H350 - H360D - H410 |
Precautionary statements | P201 - P273 - P301 + P312 + P330 - P308 + P313 |
Hazard Codes | T |
Risk Statements | 45-60-61-22-64 |
Safety Statements | 36/37/39-45 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥99% |
Storage Temp. | 2-8°C |
UNSPSC | 12161501 |