D-(+)-Trehalose dihydrate
SIGMA/T9531 - ≥99% (HPLC), from Saccharomyces cerevisiae
Synonym: Trehalose dihydrate; α,α-Trehalose; α-D-Glucopyranosyl-α-D-glucopyranoside
CAS Number: 6138-23-4
Empirical Formula (Hill Notation): C12H22O11 · 2H2O
Molecular Weight: 378.33
EC Number: 202-739-6
MDL Number: MFCD00071594
Linear Formula: C12H22O11 · 2H2O
Product Type: Chemical
| application(s) | advanced drug delivery agriculture cell analysis life science and biopharma sample preparation |
| assay | ≥99% (HPLC) |
| biological source | Saccharomyces cerevisiae |
| color | white |
| form | powder |
| impurities | ≤5.0% EtOH |
| <20 ppm Trace metals | |
| InChI | 1S/C12H22O11.2H2O/c13-1-3 |
| InChI key | DPVHGFAJLZWDOC-PVXXTIHASA |
| mp | 97-99 °C |
| optical activity | [α]20/D 174 to 182 °, c = 7% (w/v) in water |
| Quality Level | 300  |
| SMILES string | [H]O[H].[H]O[H].OC[C@H]1O |
| solubility | water: 50 mg/mL, clear, colorless |
| storage temp. | room temp |
| technique(s) | cell based assay: suitable |
| cryopreservation: suitable | |
| HPLC: suitable | |
| PCR: suitable |
| Analysis Note: | Reduced metal ion content. |
| Application: | D-(+)-Trehalose dihydrate has been used: • as a transcription factor EB (TFEB) to study its effects on an autophagy-lysosomal system in human silicosis alveolar macrophages • as stabilizing excipient in spray-dried protein formulations • as a cryoprotectant to study its effects on mouse testicular cell suspensions |
| Biochem/physiol Actions: | D-(+)-Trehalose shows anti-desiccant and cryopreservative activities. It acts as an osmolyte, and stress protectant and helps in the storage and transport of carbon. Trehalose is involved in the food, cosmetic, and pharmaceutical industries. It plays a vital role in the survival of certain insects and plants known as anhydrobionts during harsh environments such as high rates of dehydration. |
| General description: | Trehalose, also known as mycose or tremalose, is a nonreducing disaccharide of glucose commonly found in fungi, bacteria, and invertebrates. Its presence in these organisms highlights its significance in various biological processes and potential applications in biochemical research and cell culture studies. |
| Other Notes: | For additional information on our range of Biochemicals , please complete this form . |
| Other Notes: | To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page. |
| Packaging: | 10 mg in glass bottle |
| Packaging: | 2.5, 25 kg in poly drum |
| Packaging: | 5, 10, 25, 100, 500 g in poly bottle |
| Preparation Note: | Prepared by ion exchange chromatography. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% (HPLC) |
| mp | 97-99 °C |
| Storage Temp. | room temp |
| UNSPSC | 12352201 |