Trypsin-chymotrypsin inhibitor from Glycine max (soybean)
SIGMA/T9777 - lyophilized powder
Synonym: Bowman-Birk Inhibitor
CAS Number: 37330-34-0
MDL Number: MFCD00132532
Product Type: Chemical
Trypsin Inhibitor (Bowman-Birk) (soybean)
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T9777-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T9777-500MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: T9777-50MG
| biological source | Glycine max (soybean) |
| composition | Protein, 70-90% biuret |
| form | lyophilized powder |
| Quality Level | 200  |
| storage temp. | 2-8°C |
| Analysis Note: | 1 mg protein will inhibit ≥0.5 mg trypsin with activity of ~10,000 BAEE units per mg protein or ≥1.0 mg chymotrypsin with activity of ~40 BTEE units per mg protein. |
| Application: | Bowman Birk protease inhibitor prevents radiation-induced carcinogenesis by a reduction of incorrect DNA repairs, resulting in a reduced amount of dicentric chromosomes. |
| Application: | Trypsin-chymotrypsin inhibitor from Glycine max (soybean) has been used for flow cytometric separase activity assay. It has also been used to inhibit trypsin and chymotrypsin for in vitro gastrointestinal (GI) digestion studies. |
| General description: | Highly cross-linked with seven disulfide bridges, Bowman-Birk inhibitor has spatially distinct domains for trypsin and chymotrypsin inhibition. |
| General description: | Trypsin-chymotrypsin inhibitor belongs to the family of plant protease inhibitors. It is mainly found in the legume (Fabaceae) and cereal (Poaceae) families. Trypsin-chymotrypsin inhibitor consists of many internal disulfide bonds between conserved Cys residues, which maintains structural stability and active conformation of the inhibitory loops. Trypsin-chymotrypsin has anticarcinogenic properties. |
| Other Notes: | View more information on Trypsin Inhibitor . |
| Packaging: | 10 mg in glass bottle |
| Packaging: | 25 mg in poly bottle |
| Packaging: | 50, 100, 500 mg in glass bottle |
| Physical form: | Lyophilized powder containing phosphate buffer salts, pH 7.6 |
| Unit Definition: | One trypsin unit = ΔA253 of 0.001 per min with BAEE as substrate at pH 7.6 at 25 °C. Reaction volume = 3.2 mL (1 cm light path). |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352202 |