Troponin I from human heart
SIGMA/T9924 - lyophilized powder
Synonym: Tn-I
CAS Number: 77108-40-8
MDL Number: MFCD00213059
Product Type: Chemical
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| biological source | human heart |
| form | lyophilized powder |
| purified by | affinity chromatography |
| Quality Level | 200  |
| shipped in | dry ice |
| solubility | water: 5 vial/mL, clear, colorless |
| storage temp. | −20°C |
| technique(s) | inhibition assay: suitable |
| UniProt accession no. | P19429  |
| Application: | Troponin I from human heart can be used in studies whether the actin and aldolase can protect rabbit muscle lactate dehydrogenase inhibition by ascorbate or not. |
| Biochem/physiol Actions: | The inhibiting subunit of troponin, responsible for preventing actin-myosin binding and ATPase activity. |
| Biochem/physiol Actions: | Troponin I interacts with tropomyosin for regulating the contraction of striated muscle in a calcium-dependent manner. Additionally, Troponin I can also inhibits actomyosin ATPase and serves as a selective and potent inhibitor of angiogenesis in vivo and in vitro and of tumor metastasis in vivo. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |