TrueGel3D Polymer
SIGMA/TRUEPVAS - Modifed for slow gelling (SLO-PVA)
Product Type: Chemical
Cyst formation of MDCK cells in TrueGel hydrogel
| biological source | synthetic |
| shipped in | dry ice |
| storage temp. | −70°C |
| technique(s) | cell attachment: suitable |
| Application: | SLO-PVA polymer is used with crosslinkers (CD/PEG crosslinkers) to establish stable hydrogels |
| Disclaimer: | Avoid frequent freeze-thaw cycles and store SLO-PVA in small portions |
| Features and Benefits: | • Contains synthetic polymer (PVA) functionalized with thiol reactive groups for slow gelation • Non degradable polymer |
| General description: | PVA polymers are functionalized with thiol-reactive groups, which react at a slower rate with thiol groups of crosslinkers (CD/PEG crosslinkers) to form stable hydrogels. The slow gelation kinetics allows enough time to conveniently manipulate the solution before the onset of homogenous gel formation. The thioglycerol is used to maintain hydrogel strength and also as a control to compare cellular behavior in peptide-modified versus unmodified hydrogels. |
| Other Notes: | TRUEPVAS contains SLO-PVA solution in phosphate buffer, TrueGel3D thioglycerol and water |
| Symbol |  GHS05 |
| Signal word | Warning |
| Hazard statements | H290 |
| Precautionary statements | P234 - P390 |
| RIDADR | UN 1789 8 / PGIII |
| WGK Germany | WGK 3 |
| Storage Temp. | −70°C |
| UNSPSC | 12352207 |