TrueGel3D RGD
SIGMA/TRUERGD - Integrin Adhesion Peptide
Synonym: 3D cell culture matrix
Product Type: Chemical
Cyst formation of MDCK cells in TrueGel hydrogel
| shipped in | dry ice |
| storage temp. | −20°C |
| Application: | Polymer with cell adhesion motif (RGD) employed to generate cell-adhesive hydrogel |
| Features and Benefits: | Contains cell adhesion motif RGD (Acetyl-Cys-Doa*-Doa-Gly- *Doa : 8-amino-3,6-dioxaoctanoic acid |
| General description: | RGD sequences on extracellular matrix proteins (fibronectin, vitronectin) promote cell adhesion to cellular integrin receptors. The thiol group on the N-terminus of TrueGel3D® RGD peptide acts as linker to bind RGD motif to the polymer (Dextran/PVA). The conjugated RGD motif on polymer promotes adhesion of cells with appropriate integrin receptors. |
| General description: | TrueGel3D® is a commercially available polymer-based diverse array of scaffolds for 3D in vitro tumor models. The RGD peptide present in these hydrogels enable cell attachment. |
| Legal Information: | TRUEGEL3D is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Other Notes: | TRUERGD contains RGD degradable polymer lyophilized and water |
| RIDADR | NONH for all modes of transport |
| Storage Temp. | −20°C |
| UNSPSC | 12352207 |