Urease from Canavalia ensiformis (Jack bean)
SIGMA/U0251 - Type C-3, powder, ≥600,000 units/g solid
Synonym: Jack bean urease; Urea amidohydrolase
CAS Number: 9002-13-5
EC Number: 232-656-0
MDL Number: MFCD00070858
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: U0251-12KU
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: U0251-60KU
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: U0251-6KU
| biological source | Canavalia ensiformis |
| form | powder |
| mol wt | ~544620 Da |
| purified by | crystallization |
| Quality Level | 200  |
| specific activity | ≥600,000 units/g solid |
| storage temp. | −20°C |
| type | Type C-3 |
| Biochem/physiol Actions: | Urease aids in the bioavailability of nitrogen in plants. It is implicated in defense mechanism and exhibits insecticidal activity. In addition, urease exhibits antifungal activity by retarding growth and affecting membrane integrity of filamentous fungi and yeasts. |
| Biochem/physiol Actions: | Urease was shown to induce vacuolation in Hela cells, an effect dependent on the ability of urease to convert urea to ammonia. |
| General description: | Subunit molecular weight: ~90,770 Composed of six subunits with total molecular weight: ~544,620 |
| General description: | Urease is a nickel-dependent metalloenzyme , found in various plants, bacteria, fungi, and algae. It contains two distinct subunits-UreA(26.5 kDa) and UreB (60.3–61.6 kDa). |
| Packaging: | 6000, 12000, 60000 units in glass bottle |
| Unit Definition: | One micromolar unit will liberate 1.0 μmole of NH3 from urea per min at pH 7.0 at 25 °C. It is equivalent to 1.0 I.U. or 0.054 Sumner unit (1.0 mg ammonia nitrogen in 5 minutes at pH 7.0 at 20 °C) |
| Symbol |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H315 - H319 - H334 - H335 |
| Precautionary statements | P261 - P264 - P271 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 36/37/38-42 |
| Safety Statements | 22-24-26-36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| activity | specific activity: ≥600,000 units/g solid |
| Storage Temp. | −20°C |
| Enzyme Commission (EC) Number | 3.5.1.5 ( BRENDA  | IUBMB ) |
| UNSPSC | 12352204 |