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Uridine 5′-triphosphate trisodium salt solution

SIGMA/U1006 - HPLC purified, aqueous solution for RNA polymerase transcription

Synonym: UTP

MDL Number: MFCD00044310
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-U1006-25UMO 25 µmol
$118.00
1/EA
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assay ≥95 (HPLC)
biological source yeast (Candida Utilis)
color colorless
concentration 100 mM in H2O (adjusted to pH 7 with Trizma®
base)
foreign activity DNase and RNase, none detected
form liquid
InChI 1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1
InChI key MMJGIWFJVDOPJF-LLWADOMFSA-K
Quality Level 300 
shipped in dry ice
SMILES string [Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O
storage temp. −20°C
Application: Uridine 5′-triphosphate trisodium salt solution has been used to increase the intracellular Ca2+ levels in rat primary tracheal epithelial cells. It has also been used as a nucleotide substrate to analyze the activity of MutT homologue 1 (MTH1).
Biochem/physiol Actions: P2Y receptor agonist
Biochem/physiol Actions: Uridine 5′-triphosphate (UTP) is released during nerve injury and acts as an agonist of the purinergic P2Y2 receptors present on the surface of Schwann cells.
Biochem/physiol Actions: UTP plays a crucial role in the process of transcription by participating in the synthesis of RNA. It is associated with glycogen synthesis, protein glycosylation, and membrane phospholipid biosynthesis. UTP is involved in the production of ATP, which is essential for metabolic reactions.
Legal Information: Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95 (HPLC)
Storage Temp. −20°C
UNSPSC 41106305

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