Uridine 5′-triphosphate trisodium salt solution
SIGMA/U1006 - HPLC purified, aqueous solution for RNA polymerase transcription
Synonym: UTP
MDL Number: MFCD00044310
Product Type: Chemical
| assay | ≥95 (HPLC) |
| biological source | yeast (Candida Utilis) |
| color | colorless |
| concentration | 100 mM in H2O (adjusted to pH 7 with Trizma® base) |
| foreign activity | DNase and RNase, none detected |
| form | liquid |
| InChI | 1S/C9H15N2O15P3.3Na/c12-5 |
| InChI key | MMJGIWFJVDOPJF-LLWADOMFSA |
| Quality Level | 300 ![]() |
| shipped in | dry ice |
| SMILES string | [Na+].[Na+].[Na+].O[C@H]1 |
| storage temp. | −20°C |
| Application: | Uridine 5′-triphosphate trisodium salt solution has been used to increase the intracellular Ca2+ levels in rat primary tracheal epithelial cells. It has also been used as a nucleotide substrate to analyze the activity of MutT homologue 1 (MTH1). |
| Biochem/physiol Actions: | P2Y receptor agonist |
| Biochem/physiol Actions: | Uridine 5′-triphosphate (UTP) is released during nerve injury and acts as an agonist of the purinergic P2Y2 receptors present on the surface of Schwann cells. |
| Biochem/physiol Actions: | UTP plays a crucial role in the process of transcription by participating in the synthesis of RNA. It is associated with glycogen synthesis, protein glycosylation, and membrane phospholipid biosynthesis. UTP is involved in the production of ATP, which is essential for metabolic reactions. |
| Legal Information: | Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95 (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 41106305 |

