U-69593
SIGMA/U103 - solid
Synonym: (+)-(5α,7α,8β)-N-Methyl-N-[7-(1-pyrrolidinyl)-1-oxaspiro[4.5]dec-8-yl]-benzeneacetamide; U69593
CAS Number: 96744-75-1
Empirical Formula (Hill Notation): C22H32N2O2
Molecular Weight: 356.50
MDL Number: MFCD05664586
Linear Formula: C22H32N2O2
Product Type: Chemical
color | white |
form | solid |
InChI | 1S/C22H32N2O2/c1-23(21(25 |
InChI key | PGZRDDYTKFZSFR-ONTIZHBOSA |
optical activity | [α]/D +7.8°, c = 0.825 in methanol(lit.) |
Quality Level | 100 ![]() |
SMILES string | CN([C@H]1CC[C@@]2(CCCO2)C |
solubility | 0.1 M HCl: >40 mg/mL |
0.1 M NaOH: insoluble | |
45% (w/v) aq 2-hydroxypropyl-β-cyclode |
|
ethanol: >40 mg/mL | |
H2O: insoluble | |
storage temp. | 2-8°C |
Biochem/physiol Actions: | U-69593 is a selective κ opioid receptor agonist. U-69593 is known to inhibit cocaine sensitization in meso-limbic dopamine neurons by normalizing basal overflow of dopamine. |
Features and Benefits: | This compound is featured on the Opioid Receptors ![]() ![]() |
Packaging: | 25 mg in poly bottle |
Packaging: | 5 mg in glass bottle |
Preparation Note: | U-69593 is soluble in 45% (w/v) aq 2-hydroxypropyl-β-cyclode |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |