UK 14,304
SIGMA/U104
Synonym: 5-
CAS Number: 59803-98-4
Empirical Formula (Hill Notation): C11H10BrN5
Molecular Weight: 292.13
MDL Number: MFCD00153878
Linear Formula: C11H10BrN5
Product Type: Chemical
InChI | 1S/C11H10BrN5/c12-9-7(17- |
InChI key | XYLJNLCSTIOKRM-UHFFFAOYSA |
Quality Level | 100 ![]() |
SMILES string | Brc1c(NC2=NCCN2)ccc3nccnc |
solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclode |
DMSO: >6.5 mg/mL | |
ethanol: <8 mg/mL (warm) | |
H2O: insoluble |
Application: | UK 14,304 has been used for the activation of extracellular signal-regulated kinase (ERK) in epicardial coronary artery culture |
Application: | UK 14,304 has been used in myenteric neurons to study the inhibition of R-type calcium currents. UK 14,304 has also been used for immunofluorescence microscopy assays. |
Biochem/physiol Actions: | UK 14,304 is an α2-adrenoceptor agonist. UK 14,304 inhibits hormone-sensitive lipase (HSL) activity and suppresses lipogenesis in adipose tissue. |
Features and Benefits: | This compound is featured on the α2-Adrenoceptors ![]() ![]() |
Packaging: | 5, 25, 100 mg in glass bottle |
Preparation Note: | UK 14,304 is soluble in 45% (w/v) aq 2-hydroxypropyl-β-cyclode |
Symbol | ![]() |
Signal word | Danger |
Hazard statements | H301 |
Precautionary statements | P301 + P310 |
Hazard Codes | T |
Risk Statements | 25 |
Safety Statements | 45 |
RIDADR | UN 2811 6.1 / PGIII |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
UNSPSC | 12352200 |