(−)-trans-(1S,2S)-U-50488 hydrochloride hydrate
SIGMA/U111 - solid, ≥98% (HPLC)
Synonym: trans-
CAS Number: 114528-79-9 (anhydrous)
Empirical Formula (Hill Notation): C19H26Cl2N2O · HCl · xH2O
Molecular Weight: 405.79 (anhydrous basis)
MDL Number: MFCD11044455
Linear Formula: C19H26Cl2N2O · HCl · xH2O
Product Type: Chemical
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This image depicts U111-5MG.
This image depicts U111-5MG.
| assay | ≥98% (HPLC) |
| color | white |
| form | solid |
| InChI | 1S/C19H26Cl2N2O.ClH.H2O/c |
| InChI key | UWPRPWMHQDPOFR-MPGISEFESA |
| optical activity | [α]22/D -39.0 to -32.0°, c = 0.5 in methanol(lit.) |
| Quality Level | 100  |
| SMILES string | O.Cl.CN([C@H]1CCCC[C@@H]1 |
| solubility | H2O: 13 mg/mL |
| storage condition | desiccated |
| storage temp. | 2-8°C |
| Application: | (−)-trans-(1S,2S)-U-50488 hydrochloride hydrate (U-50488) has been used as a κ-opioid receptor (KOR) agonist has been used to study its effect on the increase of tidal volumes in adult red-eared slider turtles (Trachemys scripta). |
| Biochem/physiol Actions: | Potent κ opioid receptor agonist; more potent enantiomer of (±)-trans-U-50488. |
| Packaging: | 5, 25, 100 mg in glass bottle |
| Preparation Note: | (−)-trans-(1S,2S)-U-50488 hydrochloride hydrate is soluble in water at 13 mg/ml. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |