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DMT-2′O-TBDMS-rU Phosphoramidite

SIGMA/U211040 - configured for MerMade

Synonym: 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]-uridine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; DMT-2′-O-TBDMS-rU amidite

CAS Number: 118362-03-1
Empirical Formula (Hill Notation): C45H61N4O9PSi
Molecular Weight: 861.05
MDL Number: MFCD00080343
Linear Formula: C45H61N4O9PSi
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-U211040-0.5G 0.5 g
$177.00
1/EA
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45-U211040-5G 5 g
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45-U211040-10G 10 g
$0.00
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λ conforms (UV/VIS Identity)
assay ≥99% (31P-NMR)
  ≥99.0% (reversed phase HPLC)
biological source non-animal source (no BSE/TSE risk)
color white to off-white
compatibility configured for MerMade
form powder
impurities ≤0.3% water content (Karl Fischer)
  ≤0.5% P(III) Impurities 100-169ppm (31P-NMR)
  ≤0.5% single Impurity (reversed phase HPLC)
  ≤3% residual Solvent content
InChI 1S/C45H61N4O9PSi/c1-31(2)49(32(3)4)59(55-29-15-27-46)57-40-38(56-42(48-28-26-39(50)47-43(48)51)41(40)58-60(10,11)44(5,6)7)30-54-45(33-16-13-12-14-17-33,34-18-22-36(52-8)23-19-34)35-20-24-37(53-9)25-21-35/h12-14,16-26,28,31-32,38,40-42H,15,29-30H2,1-11H3,(H,47,50,51)/t38-,40-,41-,42-,59?/m1/s1
InChI key SKNLXHRBXYGJOC-ZMHKPELYSA-N
nucleoside profile base: uridine
base protecting group: none
2' protecting group: TBDMS
5' protecting group: DMT
deprotection: fast/standard
product line Proligo Reagents
Quality Level 300 
SMILES string COc1ccc(cc1)C(OC[C@H]2O[C@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)N3C=CC(=O)NC3=O)(c4ccccc4)c5ccc(OC)cc5
storage temp. −20°C
suitability conforms to structure for H-NMR
  conforms to structure for LC-MS
technique(s) oligo synthesis: suitable
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥99% (31P-NMR); ≥99.0% (reversed phase HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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