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URB597

SIGMA/U4133 - ≥98% (HPLC), powder

Synonym: Cyclohexylcarbamic acid 3ยด-carbamoyl-biphenyl-3-yl ester

CAS Number: 546141-08-6
Empirical Formula (Hill Notation): C20H22N2O3
Molecular Weight: 338.40
MDL Number: MFCD05863934
Linear Formula: C20H22N2O3
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-U4133-5MG 5 mg
$132.00
1/EA
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45-U4133-25MG 25 mg
$443.00
1/EA
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assay ≥98% (HPLC)
color white
form powder
InChI 1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)
InChI key ROFVXGGUISEHAM-UHFFFAOYSA-N
Quality Level 100 
SMILES string NC(=O)c1cccc(c1)-c2cccc(OC(=O)NC3CCCCC3)c2
solubility DMSO: soluble ~14 mg/mL
storage temp. 2-8°C
Biochem/physiol Actions: Potent, selective fatty acid amide hydrolase (FAAH) inhibitor.
General description: URB597 binds to active sites of fatty acid amide hydrolases and inhibits their activity. URB597 alters expression of tyrosine hydroxylase and interacts with abnormal-cannabidiol (Abn-CBD) and peroxisome proliferator-activated receptors (PPARs). URB597 elicits antinociception property via cannabinoid receptor by maintaining endocannabinoid anandamide (AEA) levels. URB597 reduces abnormal hyperactivity in neurons and could be for treatment of seizures and improving synaptic plasticity.
Packaging: 5, 25 mg in glass bottle
Preparation Note: URB597 is soluble in DMSO at a concentration that is approximately 14 mg/ml.
Hazard Codes N
Risk Statements 50/53
Safety Statements 22-24/25-60-61
RIDADR UN 3077 9 / PGIII
WGK Germany WGK 3
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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