Synonym: 21-[4-(2,6-Di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]pregna-1,4,9[11]-triene-3,20-dione maleate salt
CAS Number: 153190-29-5
Empirical Formula (Hill Notation): C37H50N6O2 · C4H4O4
Molecular Weight: 726.90
MDL Number: MFCD01074991
Linear Formula: C37H50N6O2 · C4H4O4
Product Type: Chemical
| InChI |
1S/C37H50N6O2.C4H4O4/c1-36-13-11-27(44)23-26(36)7-8-28-29-9-10-31(37(29,2)14-12-30(28)36)32(45)25-40-19-21-42(22-20-40)34-24-33(41-15-3-4-16-41)38-35(39-34)43-17-5-6-18-43;5-3(6)1-2-4(7)8/h11-13,23-24,28-29,31H,3-10,14-22,25H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t28-,29-,31+,36-,37-;/m0./s1 |
| InChI key |
ABCSSKWSUJMJCP-WQDFMEOSSA-N |
| SMILES string |
OC(=O)C=C/C(O)=O.[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)C1=CC[C@]4(C)[C@H](CC[C@@]24[H])C(=O)CN5CCN(CC5)c6cc(nc(n6)N7CCCC7)N8CCCC8 |
| solubility |
ethanol: soluble 20 mg/mL, clear, light yellow |
| storage temp. |
−20°C |
| Application: |
U-74389G has been shown to significantly decrease the level of ethanol-induced gastric mucosal necrosis in portal hypertensive (PHT) rats. Furthermore, U-74389G has been widely used in animal models of ischemic injury and hypertension. |
| Biochem/physiol Actions: |
Free radical lipid peroxidation inhibitor in cultured brain cells, monocytic THP1 cells, and LLC-PK1 cell layers. |
| Packaging: |
100 mg in glass insert |
| Preparation Note: |
U-74389G is soluble in ethanol at 20 mg/ml and yields a clear, light yellow solution. |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Storage Temp. |
−20°C |
| UNSPSC |
12352200 |
