Ubiquitin-Specific Protease 8 human
SIGMA/U6135 - recombinant, expressed in Sf9 cells, ≥70% (SDS-PAGE)
Product Type: Chemical
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| assay | ≥70% (SDS-PAGE) |
| concentration | ≥0.10 mg/mL protein (Bradford) |
| form | buffered aqueous glycerol solution |
| mol wt | 128 kDa |
| NCBI accession no. | NM_005154   |
| Quality Level | 200 |
| recombinant | expressed in Sf9 cells |
| shipped in | dry ice |
| storage temp. | −70°C |
| Application: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| Biochem/physiol Actions: | Expression of ubiquitin-specific protease 8 (USP8) in mice is critical for proper expression and stability of several growth factor receptors including epidermal growth factor receptor. However, USP8 was shown to degrade chemokine receptor 4. |
| General description: | Human USP8 (Ubiquitin-Specific Protease 8) or UBPY, amino-acids 2-1118 (end) with an N-terminal FLAG-tag, expressed in a baculovirus-infected Sf9 cell expression system. |
| Physical form: | Solution in 45 mM Tris-HCl, 124 mM NaCl, 2.4 mM KCl, 90 ng/μl Flag peptide, 3 mM DTT, and 20% Glycerol at pH 8.0. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥70% (SDS-PAGE) |
| Storage Temp. | −70°C |
| UNSPSC | 12352204 |