Ubiquitin-Specific Protease 8 human
SIGMA/U6135 - recombinant, expressed in Sf9 cells, ≥70% (SDS-PAGE)
Product Type: Chemical
assay | ≥70% (SDS-PAGE) |
concentration | ≥0.10 mg/mL protein (Bradford) |
form | buffered aqueous glycerol solution |
mol wt | 128 kDa |
NCBI accession no. | NM_005154 ![]() ![]() |
Quality Level | 200 ![]() |
recombinant | expressed in Sf9 cells |
shipped in | dry ice |
storage temp. | −70°C |
Application: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Biochem/physiol Actions: | Expression of ubiquitin-specific protease 8 (USP8) in mice is critical for proper expression and stability of several growth factor receptors including epidermal growth factor receptor. However, USP8 was shown to degrade chemokine receptor 4. |
General description: | Human USP8 (Ubiquitin-Specific Protease 8) or UBPY, amino-acids 2-1118 (end) with an N-terminal FLAG-tag, expressed in a baculovirus-infected Sf9 cell expression system. |
Physical form: | Solution in 45 mM Tris-HCl, 124 mM NaCl, 2.4 mM KCl, 90 ng/μl Flag peptide, 3 mM DTT, and 20% Glycerol at pH 8.0. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥70% (SDS-PAGE) |
Storage Temp. | −70°C |
UNSPSC | 12352204 |