Uvaol
SIGMA/U6628 - ≥95%
Synonym: Urs-12-ene-3,28-diol
CAS Number: 545-46-0
Empirical Formula (Hill Notation): C30H50O2
Molecular Weight: 442.72
EC Number: 208-888-3
MDL Number: MFCD00009620
Linear Formula: C30H50O2
Product Type: Chemical
| application(s) | metabolomics vitamins, nutraceuticals, and natural products |
| assay | ≥95% |
| InChI | 1S/C30H50O2/c1-19-10-15-3 |
| InChI key | XUARCIYIVXVTAE-ZAPOICBTSA |
| mp | 223-225 °C (lit.) |
| Quality Level | 100 ![]() |
| SMILES string | C[C@@H]1CC[C@]2(CO)CC[C@] |
| Application: | Uvaol has been used as retinoic acid receptor-related orphan receptor gamma t (RORγt) inhibitor to study the role of cardiac glycoside reductase 2 (Cgr2) enzyme on its metabolism. |
| Biochem/physiol Actions: | Uvaolexerts pharmacological properties such as antioxidant, anticancer, anti-inflammatory, and wound healing. It also displays vasodilator, hepatoprotective, and antimicrobial effects. Uvaol has inhibitory effects on nitric oxide (NO) release. |
| General description: | Uvaolis a pentacyclic triterpene compound usually extracted from plant leaves such as Apocynum venetum L., olive leaves (Olea europaea L.), and oregano (Origanum vulgare L.). |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% |
| mp | 223-225 °C (lit.) |
| UNSPSC | 12352103 |

