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Uridine 5′-triphosphate trisodium salt hydrate

SIGMA/U6750 - Type IV, ≥93.0% (HPLC)

Synonym: UTP Na3

CAS Number: 19817-92-6 (anhydrous)
Empirical Formula (Hill Notation): C9H12N2Na3O15P3 · xH2O
Molecular Weight: 550.09 (anhydrous basis)
EC Number: 243-347-5
MDL Number: MFCD00044310
Linear Formula: C9H12N2Na3O15P3 · xH2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-U6750-100MG 100 mg
 $58.20
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45-U6750-250MG 250 mg
 $97.20
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45-U6750-500MG 500 mg
 $168.00
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45-U6750-1G 1 g
 $295.00
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assay ≥93.0% (HPLC)
InChI 1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1
InChI key MMJGIWFJVDOPJF-LLWADOMFSA-K
Quality Level 200 
SMILES string [Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O
solubility H2O: soluble 25 mg of UTP in 0.5 ml of solvent, clear, colorless
storage temp. −20°C
type Type IV
Application: Uridine 5′-triphosphate has been used in a study to show that fluoxetine (FLX), mediates its anti-depressive effect by increasing the gliotransmission of adenosine 5′-triphosphate (ATP).
Application: UTP has been used as a P2 receptor activator to study its effects on proton efflux in MC3T3-E1 and UMR-106 cells. UTP has also been studied in combination with amiloride hydrochloride in nebulizer solutions for treating cystic fibrosis.
Biochem/physiol Actions: P2Y receptor agonist.
Biochem/physiol Actions: Uridine-5′-Triphosphate (UTP) is a cytosolic nucleotide component of nucleic acids. It serves as a signaling molecule in the extracellular space. Uridine-5′-Triphosphate (UTP) is involved in various pathophysiological responses in the nervous system. UTP also plays a major role in the regeneration process.
Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
Preparation Note: 25 mg of Uridine 5′-triphosphate trisodium salt (UTP Na3) hydrate is soluble in 0.5 ml of water and yields a clear, colorless solution.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥93.0% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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