Ubiquitin-Carrier Protein H10 human
SIGMA/U9382 - ≥95% (SDS-PAGE), recombinant, expressed in E. coli (histidine-tagged), buffered aqueous glycerol solution
Synonym: UbcH10
MDL Number: MFCD03458906
Product Type: Chemical
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| assay | ≥95% (SDS-PAGE) |
| biological source | human |
| form | buffered aqueous glycerol solution |
| mol wt | ~20 kDa |
| Quality Level | 200  |
| recombinant | expressed in E. coli (histidine-tagged) |
| shipped in | dry ice |
| storage temp. | −70°C |
| technique(s) | ligand binding assay: suitable |
| UniProt accession no. | O00762  |
| Application: | Ubiquitin-Carrier Protein H10 (UbcH10) human may be used to study the role of ubiquitin-proteasome system in pathogenesis of human diseases. |
| Biochem/physiol Actions: | In conjunction with anaphase-promoting complex, catalyzes both cyclin A and cyclin B destruction. |
| Biochem/physiol Actions: | In conjunction with the anaphase-promoting complex, the protein catalyzes the destruction of both cyclin A and cyclin B. |
| Biochem/physiol Actions: | Ubiquitin-Carrier Protein H10 human also referred to as UbcH10 is a recombinant protein that catalyzes the destruction of cyclin A as well as cyclin B along with the anaphase promoting complex and hence plays a pivotal role in controlling the cell exit from mitosis. |
| General description: | Manufactured for Sigma by Boston Biochem., Inc. |
| Physical form: | Solution in 50 mM HEPES, pH 8.0, 125 mM NaCl, and 1 mM DTT in 10% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | 235.4 °F - closed cup |
| Flash Point(C) | 113 °C - closed cup |
| Purity | ≥95% (SDS-PAGE) |
| Storage Temp. | −70°C |
| UNSPSC | 12352202 |