4-Hydroxytolbutamide
SIGMA/UC160 - ≥98% (HPLC)
Synonym: N-
CAS Number: 5719-85-7
Empirical Formula (Hill Notation): C12H18N2O4S
Molecular Weight: 286.35
MDL Number: MFCD00144466
Linear Formula: C12H18N2O4S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white |
form | solid |
InChI | 1S/C12H18N2O4S/c1-2-3-8-1 |
InChI key | SJRHYONYKZIRPM-UHFFFAOYSA |
mp | 100-102 °C |
SMILES string | CCCCNC(=O)NS(=O)(=O)c1ccc |
solubility | 0.1 M NaOH: soluble 4 mg/mL |
ethanol: soluble 12 mg/mL | |
H2O: insoluble | |
storage temp. | 2-8°C |
Application: | 4-Hydroxytolbutamide has been used as a standard to assay the fungal biotransformation of tolbutamide to 4′-hydroxytolbutamide. |
Other Notes: | Metabolite of tolbutamide; formed by the cytochrome CYP2CIIC8 and IIC9 subfamily of P450 enzymes. |
Packaging: | 5, 10 mg in glass bottle |
Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
Preparation Note: | 4-Hydroxytolbutamide is soluble in ethanol at 12 mg/mL and is also soluble in 0.1 M NaOH at 4 mg/ml. It is insoluble in water. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
mp | 100-102 °C |
Storage Temp. | 2-8°C |
UNSPSC | 12161501 |