(±)-Bufuralol hydrochloride
SIGMA/UC168
Synonym: α-[(tert-Butylamino)methyl]-7-ethyl-2-benzofuranmethanol hydrochloride
CAS Number: 60398-91-6
Empirical Formula (Hill Notation): C16H23NO2·HCl
Molecular Weight: 297.82
EC Number: 262-216-3
MDL Number: MFCD00272648
Linear Formula: C16H23NO2·HCl
Product Type: Chemical
color | white to off-white |
form | solid |
InChI | 1S/C16H23NO2.ClH/c1-5-11- |
InChI key | KJBONRGCLLBWCJ-UHFFFAOYSA |
mp | 143-146 °C |
Quality Level | 200 |
SMILES string | Cl.CCc1cccc2cc(oc12)C(O)C |
solubility | H2O: soluble |
methanol: soluble | |
storage temp. | 2-8°C |
Application: | CYP2D6 substrate |
Biochem/physiol Actions: | β-Blocker. Varying β-adrenoceptor agonist/antagonist activity. |
Biochem/physiol Actions: | Bufuralol hydrochloride is known to be a non-specific β-receptor inhibitor that has an affinity for β 1 and β 2 receptors. Furthermore, studies have reported that bufuralol hydrochloride can decrease isoproterenol peripheral resistance. |
Features and Benefits: | This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
Packaging: | 5, 10 mg in glass bottle |
Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
Preparation Note: | (±)-Bufuralol hydrochloride is soluble in water and methanol. |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Hazard Codes | Xn |
Risk Statements | 22 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
mp | 143-146 °C |
Storage Temp. | 2-8°C |
UNSPSC | 12161501 |