O-Desmethyltramadol
SIGMA/UC304
Synonym: 2-
CAS Number: 80456-81-1
Empirical Formula (Hill Notation): C15H23NO2
Molecular Weight: 249.35
MDL Number: MFCD01311883
Linear Formula: C15H23NO2
Product Type: Chemical
| form | solid |
| InChI | 1S/C15H23NO2/c1-16(2)11-1 |
| InChI key | UWJUQVWARXYRCG-HIFRSBDPSA |
| Quality Level | 200  |
| SMILES string | CN(C)C[C@H]1CCCC[C@]1(O)c |
| storage temp. | 2-8°C |
| Application: | O-Desmethyltramadol has been used for the pharmacokinetic studies of tramadol metabolites in goats. |
| Application: | O-Desmethyltramadol may be used as an opioid to test its effect on the cytotoxic functionality of human natural killer cells. It may also be used as an internal standard in gas chromatography-mass spectrometry (GC-MS) for the quantification of tramadol based derivatives from human urine samples. |
| Biochem/physiol Actions: | O-Desmethyltramadol has a high affinity towards opioid receptors and is responsible for the analgesic effect of the μ-opioid receptor |
| Biochem/physiol Actions: | Metabolite of tramadol |
| General description: | O-Desmethyltramadol, an opioid, is an active metabolite of tramadol. The enzyme key for its production is polymorphic cytochrome P450 isoenzyme 2D6 (CYP2D6). |
| Packaging: | 5 mg in glass bottle |
| Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12161501 |