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[Arg8]-Vasopressin solution

SIGMA/V0377 - Grade VI (synthetic), ~100 IU/mL in 0.9% NaCl

Synonym: β-Hypophamine; AVP; Antidiuretic hormone; Arginine vasopressin

CAS Number: 113-79-1
Empirical Formula (Hill Notation): C46H65N15O12S2
Molecular Weight: 1084.23
MDL Number: MFCD00076738
Linear Formula: C46H65N15O12S2
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-V0377-50IU 50 I.U.
$103.00
1/EA
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45-V0377-100IU 100 I.U.
$180.00
1/EA
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biological source synthetic (organic)
concentration ~100 IU/mL in 0.9% NaCl
contains 0.4% 4-chlorobutanol as preservative
form liquid
InChI 1S/C46H65N15O12S2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53)
InChI key KBZOIRJILGZLEJ-UHFFFAOYSA-N
pH ~3.5
Quality Level 200 
shipped in ambient
SMILES string NC1CSSCC(NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(Cc2ccccc2)NC(=O)C(Cc3ccc(O)cc3)NC1=O)C(=O)N4CCCC4C(=O)NC(CCCNC(N)=N)C(=O)NCC(N)=O
sterility non-sterile
storage temp. 2-8°C
type Grade VI (synthetic)
UniProt accession no. P01185 
Amino Acid Sequence: Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 [Disulfide Bridge: 1-6]
Application: [Arg8]-Vasopressin solution was used as an antigen for preparing preadsorbed antisera for immunocytochemistry. The product was used in L6 cell culture of the C5 subclone for differentiation studies.
Biochem/physiol Actions: Endogenous antidiuretic hormone in most mammalian species. It is released into the blood from nerve terminals in the posterior pituitary and median eminence. Arg8-vasopressin is also a neurotransmitter in the central nervous system. It is implicated in a variety of physiological processes including diuresis, vasoregulation, and memory. Regulates water balance by antidiuretic action; contracts arterioles (vasopressor action).
Biochem/physiol Actions: [Arg8]-Vasopressin solution also known as Antidiuretic hormone, Arginine vasopressin or beta-Hypophamine is a selective and potent vasopressor agent that stabilizes the cardiocirculatory function in normal human as well as in patients suffering from catecholamine-resistant vasodilatory shock. It stimulates three acid-base transporters and hence increases the capability of the cell to regulate pH.
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) 235.4 °F - closed cup
Flash Point(C) 113 °C - closed cup
Storage Temp. 2-8°C
UNSPSC 51111800

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