Vancomycin hydrochloride from Streptomyces orientalis

SIGMA/V1130 - BioReagent, suitable for plant cell culture

CAS Number: 1404-93-9
Empirical Formula (Hill Notation): C₆₆H₇₅Cl₂N₉O₂₄ · HCl
Molecular Weight: 1485.71
Linear Formula: C₆₆H₇₅Cl₂N₉O₂₄ · HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-V1130-1G	1 g	$279.00 1/EA	Add To Favorites
45-V1130-5G	5 g	$1090.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: V1130-1G

Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	Gram-positive bacteria
application(s)	agriculture
biological source	Streptomyces orientalis
color	, off-white to brown or White to orange-brown
concentration	≥900 μg/mg (as vancomycin base)
form	powder
InChI	1S/C66H75Cl2N9O24.ClH/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4,70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92;/h6-11,13-19,23-24,34-35,42,44,46-54,56-57,65,71,78-81,83-87H,12,20-22,70H2,1-5H3,(H2,69,82)(H,72,92)(H,73,89)(H,74,91)(H,75,93)(H,76,88)(H,77,90)(H,94,95);1H/t24-,34+,35-,42+,44-,46+,47+,48-,49+,50-,51+,52+,53+,54-,56+,57+,65-,66-;/m0./s1
InChI key	LCTORFDMHNKUSG-XTTLPDOESA-N
mode of action	cell wall synthesis \| interferes
product line	BioReagent
Quality Level	200
SMILES string	Cl[H].CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]2C[C@](C)(N)[C@@H](O)[C@@H](C)O2.CN[C@H](CC(C)C)C(=O)NC3[C@H](O)c4ccc(Oc5cc6Oc7ccc(cc7Cl)[C@@H](O)[C@H]8NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC3=O)c(c5)c6)c9ccc(O)c(c9)-c%10c(O)cc(O)cc%10[C@@H](NC8=O)C(O)=O)c(Cl)c4
solubility	H₂O: 50 mg/mL, clear, colorless to dark yellow (and Very Faint Orange to Faint Orange)
storage condition	(Keep container tightly closed in a dry and well-ventilated place.)
storage temp.	2-8°C
technique(s)	cell culture \| plant: suitable

Application:	Vancomycin hydrochloride from Streptomyces orientalis has been used as: • an antibiotic in screening: minimal inhibitory concentrations (MICs) Streptomyces coelicolor • in treating Leishmania infected sand flies • in combined antibiotic treatment in asthma induced mice
Biochem/physiol Actions:	Mode of action: Inhibits incorporation of terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides. Antimicrobial Spectrum: Active against Gram-positive bacteria
Biochem/physiol Actions:	Vancomycin is used for treating methicillin-resistant Staphylococcus aureus (MRSA) infections and shunt-associated Staphylococcal ventriculitis. It may lead to hypersensitivity reactions like anaphylaxis and red man syndrome. Vanomycin is also used to treat thrombocytopenia and induces drug reaction with eosinophilia and systemic symptoms (DRESS) on usage.
General description:	Chemical structure: glycopeptide
General description:	Vancomycin is a heptapeptide.
Other Notes:	Keep container tightly closed in a dry and well-ventilated place.
Packaging:	1, 5 g in glass bottle

Symbol	GHS08
Signal word	Danger
Hazard statements	H317 - H334
Precautionary statements	P261 - P272 - P280 - P284 - P302 + P352 - P304 + P340 + P312
Hazard Codes	Xi
Risk Statements	43
Safety Statements	36/37
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	2-8°C
UNSPSC	10171502

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