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Vancomycin hydrochloride from Streptomyces orientalis

SIGMA/V1130 - BioReagent, suitable for plant cell culture

CAS Number: 1404-93-9
Empirical Formula (Hill Notation): C66H75Cl2N9O24 · HCl
Molecular Weight: 1485.71
Linear Formula: C66H75Cl2N9O24 · HCl
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-V1130-1G 1 g
$272.00
1/EA
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45-V1130-5G 5 g
$1060.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: V1130-1G

 

antibiotic activity spectrum Gram-positive bacteria
application(s) agriculture
biological source Streptomyces orientalis
color , off-white to brown or White to orange-brown
concentration ≥900 μg/mg (as vancomycin base)
form powder
mode of action cell wall synthesis | interferes
product line BioReagent
Quality Level 200 
SMILES string Cl[H].CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]2C[C@](C)(N)[C@@H](O)[C@@H](C)O2.CN[C@H](CC(C)C)C(=O)NC3[C@H](O)c4ccc(Oc5cc6Oc7ccc(cc7Cl)[C@@H](O)[C@H]8NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC3=O)c(c5)c6)c9ccc(O)c(c9)-c%10c(O)cc(O)cc%10[C@@H](NC8=O)C(O)=O)c(Cl)c4
solubility H2O: 50 mg/mL, clear, colorless to dark yellow (and Very Faint Orange to Faint Orange)
storage condition (Keep container tightly closed in a dry and well-ventilated place.)
storage temp. 2-8°C
technique(s) cell culture | plant: suitable
Application: Vancomycin hydrochloride from Streptomyces orientalis has been used as:
• an antibiotic in screening: minimal inhibitory concentrations (MICs) Streptomyces coelicolor
• in treating Leishmania infected sand flies
• in combined antibiotic treatment in asthma induced mice

Biochem/physiol Actions: Glycopeptide antibiotic
Mode of action: Used to block bacterial cell wall biosynthesis at the level of peptidoglycan biosynthesis by inhibiting incorporation of terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides.
Antimicrobial spectrum: Gram-positive bacteria
Biochem/physiol Actions: Vancomycin is used for treating methicillin-resistant Staphylococcus aureus (MRSA) infections and shunt-associated Staphylococcal ventriculitis. It may lead to hypersensitivity reactions like anaphylaxis and red man syndrome. Vanomycin is also used to treat thrombocytopenia and induces drug reaction with eosinophilia and systemic symptoms (DRESS) on usage.
General description: Chemical structure: glycopeptide
General description: Vancomycin is a heptapeptide.
Other Notes: Keep container tightly closed in a dry and well-ventilated place.
Packaging: 1, 5 g in glass bottle
Storage Temp. 2-8°C
UNSPSC 12352200

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